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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA

Fig. 2

a, b Cerebral cortex cryosections double immunolabeled for γH2AX and GFAP (a) or Iba1 (b) showing the absence of PDDF in an astrocyte and a microglial cell from irradiated rats at 15 days post-IR. Some neuronal nuclei of different size counterstained with DAPI contain γH2AX-positive PDDF. c Cerebral cortex cryosection illustrating a ß-galactosidase-positive senescent microglial cell free of γH2AX-positive PDDF at 15 days post-IR. Scale bars: 10 μm

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