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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA

Fig. 1

a-c Representative examples of immunolabeling for γH2AX of cortical neurons in a dissociated neuron preparation (a) and cryosections (b, c) counterstained with propidium iodide (PI) from irradiated rat (a, b) and mouse (c) at 15 days post-IR. Note the presence of typical PDDF associated with the nucleolus. d, e Rat cerebral cortex cryosections double immunolabeled for γH2AX and NeuN illustrate the specific localization of PDDF in NeuN-positive neurons at 15 days post-IR. Scale bars: a-c, e, 5 μm; d, 10 μm

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