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Table 2 Correlations of phospho-TDP-43 and DPR burden with neurodegeneration

From: Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease

 

FCtx

DF

CA4

poly-GA

r = − 0.19

r = 0.20

r = 0.10

p = 0.28

p = 0.24

p = 0.57

poly-GP

r = − 0.14

r = 0.26

r = 0.31

p = 0.42

p = 0.12

p = 0.06

poly-GR

r = 0.45

r = 0.33

r = − 0.01

p = 0.004

p = 0.04

p = 0.96

pTDP-43

r = 0.46

r = 0.40

r = 0.61

p = 0.004

p = 0.013

p = 0.00006

  1. P-values are from Pearson’s test of correlation. Significant p-values (< 0.05)
  2. FCtx frontal cortex, DF dentate fascia, CA4 cornu ammonis sector 4