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Table 2 Correlations of phospho-TDP-43 and DPR burden with neurodegeneration

From: Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease

  FCtx DF CA4
poly-GA r = − 0.19 r = 0.20 r = 0.10
p = 0.28 p = 0.24 p = 0.57
poly-GP r = − 0.14 r = 0.26 r = 0.31
p = 0.42 p = 0.12 p = 0.06
poly-GR r = 0.45 r = 0.33 r = − 0.01
p = 0.004 p = 0.04 p = 0.96
pTDP-43 r = 0.46 r = 0.40 r = 0.61
p = 0.004 p = 0.013 p = 0.00006
  1. P-values are from Pearson’s test of correlation. Significant p-values (< 0.05)
  2. FCtx frontal cortex, DF dentate fascia, CA4 cornu ammonis sector 4