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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease

Fig. 3

Colocalization of poly-GR and aDMA. Poly-GR neuronal cytoplasmic inclusions in the dentate fascia and CA4 of the hippocampus. Sparse poly-GR inclusions in the dentate fascia show colocalization with aDMA (arrow). Note that not all poly-GR aggregates contain aDMA (arrowheads) (a). Moderate poly-GR inclusions show colocalization with aDMA in CA4 (arrows). Again, not all poly-GR aggregates contain aDMA (arrowheads) (b). Scale bars: 10 μm. Plot shows the association of poly-GR and aDMA neuronal inclusions in the dentate fascia. The line shows linear regression (r = 0.77) (c)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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