TY - JOUR AU - Aguzzi, A. AU - Barres, B. A. AU - Bennett, M. L. PY - 2013 DA - 2013// TI - Microglia: scapegoat, saboteur, or something else? JO - Science VL - 339 UR - https://doi.org/10.1126/science.1227901 DO - 10.1126/science.1227901 ID - Aguzzi2013 ER - TY - JOUR AU - Akiyama, H. AU - Tago, H. AU - Itagaki, S. AU - McGeer, P. L. PY - 1990 DA - 1990// TI - Occurrence of diffuse amyloid deposits in the presubicular parvopyramidal layer in Alzheimer’s disease JO - Acta Neuropathol VL - 79 UR - https://doi.org/10.1007/BF00296114 DO - 10.1007/BF00296114 ID - Akiyama1990 ER - TY - JOUR AU - Andrew, R. J. AU - Kellett, K. A. B. AU - Thinakaran, G. AU - Hooper, N. M. PY - 2016 DA - 2016// TI - A Greek tragedy: the growing complexity of Alzheimer amyloid precursor protein proteolysis JO - J Biol Chem VL - 291 UR - https://doi.org/10.1074/jbc.R116.746032 DO - 10.1074/jbc.R116.746032 ID - Andrew2016 ER - TY - JOUR AU - Augustinack, J. C. AU - Helmer, K. AU - Huber, K. E. AU - Kakunoori, S. AU - Zöllei, L. AU - Fischl, B. PY - 2010 DA - 2010// TI - Direct visualization of the perforant pathway in the human brain with ex vivo diffusion tensor imaging JO - Front Hum Neurosci VL - 4 UR - https://doi.org/10.3389/fnhum.2010.00042 DO - 10.3389/fnhum.2010.00042 ID - Augustinack2010 ER - TY - STD TI - Bland J, Regression Analysis AD (1986) Lancet:908–909 ID - ref5 ER - TY - JOUR AU - Bliss, E. AU - Heywood, W. E. AU - Benatti, M. AU - Sebire, N. J. AU - Mills, K. PY - 2016 DA - 2016// TI - An optimised method for the proteomic profiling of full thickness human skin JO - Biol Proced Biological Procedures Online VL - 18 UR - https://doi.org/10.1186/s12575-016-0045-y DO - 10.1186/s12575-016-0045-y ID - Bliss2016 ER - TY - JOUR AU - Bobinski, M. AU - Wegiel, J. AU - Wisniewski, H. M. AU - Tarnawski, M. AU - Reisberg, B. AU - Mlodzik, B. PY - 1995 DA - 1995// TI - Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease JO - Dementia VL - 6 ID - Bobinski1995 ER - TY - JOUR AU - Boche, D. AU - Perry, V. H. AU - Nicoll, J. A. PY - 2013 DA - 2013// TI - Review: activation patterns of microglia and their identification in the human brain JO - Neuropathol Appl Neurobiol VL - 39 UR - https://doi.org/10.1111/nan.12011 DO - 10.1111/nan.12011 ID - Boche2013 ER - TY - JOUR AU - Braak, H. AU - Braak, E. PY - 1991 DA - 1991// TI - Neuropathological stageing of Alzheimer-related changes JO - Acta Neuropathol VL - 82 UR - https://doi.org/10.1007/BF00308809 DO - 10.1007/BF00308809 ID - Braak1991 ER - TY - JOUR AU - Caballero-Bleda, M. AU - Witter, M. P. PY - 1994 DA - 1994// TI - Projections from the presubiculum and the parasubiculum to morphologically characterized entorhinal-hippocampal projection neurons in the rat JO - Exp Brain Res VL - 101 UR - https://doi.org/10.1007/BF00243220 DO - 10.1007/BF00243220 ID - Caballero-Bleda1994 ER - TY - JOUR AU - Chávez-Gutiérrez, L. AU - Bammens, L. AU - Benilova, I. AU - Vandersteen, A. AU - Benurwar, M. AU - Borgers, M. PY - 2012 DA - 2012// TI - The mechanism of γ-secretase dysfunction in familial Alzheimer disease JO - EMBO J VL - 31 UR - https://doi.org/10.1038/emboj.2012.79 DO - 10.1038/emboj.2012.79 ID - Chávez-Gutiérrez2012 ER - TY - JOUR AU - Cimino, P. J. AU - Sokal, I. AU - Leverenz, J. AU - Fukui, Y. AU - Montine, T. J. PY - 2009 DA - 2009// TI - DOCK2 is a microglial specific regulator of central nervous system innate immunity found in normal and Alzheimer’s disease brain JO - Am J Pathol VL - 175 UR - https://doi.org/10.2353/ajpath.2009.090443 DO - 10.2353/ajpath.2009.090443 ID - Cimino2009 ER - TY - JOUR AU - Cork, L. AU - Masters, C. AU - Beyreuther, K. AU - Price, D. PY - 1990 DA - 1990// TI - Development of senile plaques. Relationships of neuronal abnormalities and amyloid deposits JO - Am J Pathol VL - 137 ID - Cork1990 ER - TY - JOUR AU - Cornely, R. AU - Pollock, A. H. AU - Rentero, C. AU - Norris, S. E. AU - Alvarez-Guaita, A. AU - Grewal, T. PY - 2016 DA - 2016// TI - Annexin A6 regulates interleukin-2-mediated T-cell proliferation JO - Immunol Cell Biol VL - 94 UR - https://doi.org/10.1038/icb.2016.15 DO - 10.1038/icb.2016.15 ID - Cornely2016 ER - TY - JOUR AU - Coull J a, M. AU - Beggs, S. AU - Boudreau, D. AU - Boivin, D. AU - Tsuda, M. AU - Inoue, K. PY - 2005 DA - 2005// TI - BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain JO - Nature VL - 438 UR - https://doi.org/10.1038/nature04223 DO - 10.1038/nature04223 ID - Coull J a2005 ER - TY - JOUR AU - Davalos, D. AU - Grutzendler, J. AU - Yang, G. AU - Kim, J. V. AU - Zuo, Y. AU - Jung, S. PY - 2005 DA - 2005// TI - ATP mediates rapid microglial response to local brain injury in vivo JO - Nat Neurosci VL - 8 UR - https://doi.org/10.1038/nn1472 DO - 10.1038/nn1472 ID - Davalos2005 ER - TY - JOUR AU - Drexel, M. AU - Kirchmair, E. AU - Sperk, G. PY - 2013 DA - 2013// TI - Changes in the expression of GABAA receptor subunit mRNAs in parahippocampal areas after kainic acid induced seizures JO - Front Neural Circuits VL - 7 UR - https://doi.org/10.3389/fncir.2013.00142 DO - 10.3389/fncir.2013.00142 ID - Drexel2013 ER - TY - STD TI - Efthymiou AG, Goate AM (2017) Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk. Mol Neurodegener 12. https://doi.org/10.1186/s13024-017-0184-x ID - ref18 ER - TY - JOUR AU - Eue, I. AU - König, S. AU - Pior, J. AU - Sorg, C. PY - 2002 DA - 2002// TI - S100A8, S100A9 and the S100A8/A9 heterodimer complex specifically bind to human endothelial cells: identification and characterization of ligands for the myeloid-related proteins S100A9 and S100A8/A9 on human dermal microvascular endothelial cell line-1 c JO - Int Immunol VL - 14 UR - https://doi.org/10.1093/intimm/14.3.287 DO - 10.1093/intimm/14.3.287 ID - Eue2002 ER - TY - JOUR AU - Fotinopoulou, A. AU - Tsachaki, M. AU - Vlavaki, M. AU - Poulopoulos, A. AU - Rostagno, A. AU - Frangione, B. PY - 2005 DA - 2005// TI - BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid β(Aβ) production JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.C500231200 DO - 10.1074/jbc.C500231200 ID - Fotinopoulou2005 ER - TY - STD TI - Fukutani Y, Cairns N, Rossor M, Isaki K, Lantos P (1997) Cerebellar pathology in sporadic and familial Alzheimer’s disease: a morphometric investigation. 149:177–184 Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1750-3639.1997.tb01009.x. UR - https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1750-3639.1997.tb01009.x ID - ref21 ER - TY - JOUR AU - Ghiso, J. AU - Frangione, B. PY - 2002 DA - 2002// TI - Amyloidosis and Alzheimer’s disease JO - Adv Drug Deliv Rev VL - 54 UR - https://doi.org/10.1016/S0169-409X(02)00149-7 DO - 10.1016/S0169-409X(02)00149-7 ID - Ghiso2002 ER - TY - JOUR AU - Ghiso, J. AU - Rostagno, A. AU - Tomidokoro, Y. AU - Lashley, T. AU - Bojsen-Møller, M. AU - Braendgaard, H. PY - 2006 DA - 2006// TI - Genetic alterations of the BRI2 gene: familial British and Danish dementias JO - Brain Pathol VL - 16 UR - https://doi.org/10.1111/j.1750-3639.2006.tb00563.x DO - 10.1111/j.1750-3639.2006.tb00563.x ID - Ghiso2006 ER - TY - JOUR AU - Gjoneska, E. AU - Pfenning, A. R. AU - Mathys, H. AU - Quon, G. AU - Kundaje, A. AU - Tsai, L. -. H. PY - 2015 DA - 2015// TI - Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/‘s disease JO - Nature VL - 518 UR - https://doi.org/10.1038/nature14252 DO - 10.1038/nature14252 ID - Gjoneska2015 ER - TY - JOUR AU - Gundersen, H. AU - Bendtsen, T. AU - Korbo, L. AU - Marcussen, N. AU - Moller, A. AU - Nielsen, K. PY - 1988 DA - 1988// TI - Some new, simple and efficient stereological methods and their use in pathological research and diagnosis JO - APMIS VL - 96 UR - https://doi.org/10.1111/j.1699-0463.1988.tb05320.x DO - 10.1111/j.1699-0463.1988.tb05320.x ID - Gundersen1988 ER - TY - JOUR AU - He, S. AU - Li, X. AU - Li, R. AU - Fang, L. AU - Sun, L. AU - Wang, Y. PY - 2016 DA - 2016// TI - Annexin A2 modulates ROS and Impacts inflammatory response via IL-17 signaling in Polymicrobial Sepsis mice JO - PLoS Pathog VL - 12 UR - https://doi.org/10.1371/journal.ppat.1005743 DO - 10.1371/journal.ppat.1005743 ID - He2016 ER - TY - JOUR AU - Hébert, S. S. AU - Serneels, L. AU - Dejaegere, T. AU - Horré, K. AU - Dabrowski, M. AU - Baert, V. PY - 2004 DA - 2004// TI - Coordinated and widespread expression of γ-secretase in vivo: evidence for size and molecular heterogeneity JO - Neurobiol Dis VL - 17 UR - https://doi.org/10.1016/j.nbd.2004.08.002 DO - 10.1016/j.nbd.2004.08.002 ID - Hébert2004 ER - TY - JOUR AU - Herzig, M. C. AU - Winkler, D. T. AU - Burgermeister, P. AU - Pfeifer, M. AU - Kohler, E. AU - Schmidt, S. D. PY - 2004 DA - 2004// TI - Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis JO - Nat Neurosci VL - 7 UR - https://doi.org/10.1038/nn1302 DO - 10.1038/nn1302 ID - Herzig2004 ER - TY - JOUR AU - Hessian, P. A. AU - Fisher, L. PY - 2001 DA - 2001// TI - The heterodimeric complex of MRP-8 (S100A8) and MRP-14 (S100A9) antibody recognition, epitope definition and the implications for structure JO - Eur J Biochem VL - 268 UR - https://doi.org/10.1046/j.1432-1327.2001.01894.x DO - 10.1046/j.1432-1327.2001.01894.x ID - Hessian2001 ER - TY - STD TI - Holton JL, Ghiso J, Lashley T, Rostagno A, Guerin CJ, Gibb G, et al (2001) Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. Am J Pathol Am Soc Invest Pathol 158(2):515–526. Available from: https://www.ncbi.nlm.nih.gov/pubmed/11159188. UR - https://www.ncbi.nlm.nih.gov/pubmed/11159188 ID - ref30 ER - TY - JOUR AU - Holton, J. L. AU - Lashley, T. AU - Ghiso, J. AU - Braendgaard, H. AU - Vidal, R. AU - Guerin, C. J. PY - 2002 DA - 2002// TI - Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta JO - J Neuropathol Exp Neurol VL - 61 UR - https://doi.org/10.1093/jnen/61.3.254 DO - 10.1093/jnen/61.3.254 ID - Holton2002 ER - TY - JOUR AU - Itagaki, S. AU - McGeer, P. AU - Akiyama, H. AU - Zhu, S. AU - Selkoe, D. PY - 1989 DA - 1989// TI - Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease JO - J Neuroimmunol VL - 24 UR - https://doi.org/10.1016/0165-5728(89)90115-X DO - 10.1016/0165-5728(89)90115-X ID - Itagaki1989 ER - TY - JOUR AU - Iwatsubo, T. AU - Saido, T. C. AU - Mann, D. M. AU - Lee, V. M. AU - Trojanowski, J. Q. PY - 1996 DA - 1996// TI - Full-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques JO - Am. J Pathol VL - 149 UR - https://doi.org/10.1002/ejoc.201001502 DO - 10.1002/ejoc.201001502 ID - Iwatsubo1996 ER - TY - JOUR AU - Jarrett, J. AU - Berger, E. AU - Lansbury, P. PY - 1993 DA - 1993// TI - The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer’s disease JO - Biochemistry VL - 32 UR - https://doi.org/10.1021/bi00069a001 DO - 10.1021/bi00069a001 ID - Jarrett1993 ER - TY - JOUR AU - Jarrett, J. T. AU - Lansburry, P. T. PY - 1993 DA - 1993// TI - Seeding “one dimensional cristallization” of amyloid: a pathogenic mechanism in Alzheimer’s disease and scrapie? JO - Cell VL - 73 UR - https://doi.org/10.1016/0092-8674(93)90635-4 DO - 10.1016/0092-8674(93)90635-4 ID - Jarrett1993 ER - TY - JOUR AU - Ji, B. AU - Chen, C. J. AU - Bando, K. AU - Ashino, H. AU - Shiraishi, H. AU - Sano, H. PY - 2015 DA - 2015// TI - Distinct binding of amyloid imaging ligands to unique amyloid-β deposited in the presubiculum of Alzheimer’s disease JO - J Neurochem VL - 135 UR - https://doi.org/10.1111/jnc.13293 DO - 10.1111/jnc.13293 ID - Ji2015 ER - TY - JOUR AU - Kalus, P. AU - Braak, H. AU - Braak, E. AU - Bohl, J. PY - 1989 DA - 1989// TI - The presubicular region in Alzheimer’s disease: topography of amyloid deposits and neurofibrillary changes JO - Brain Res VL - 494 UR - https://doi.org/10.1016/0006-8993(89)90164-9 DO - 10.1016/0006-8993(89)90164-9 ID - Kalus1989 ER - TY - JOUR AU - Kettenmann, H. AU - Hanisch, U. -. K. AU - Noda, M. AU - Verkhratsky, A. PY - 2011 DA - 2011// TI - Physiology of microglia JO - Physiol Rev VL - 91 UR - https://doi.org/10.1152/physrev.00011.2010 DO - 10.1152/physrev.00011.2010 ID - Kettenmann2011 ER - TY - JOUR AU - Korzhevskii, D. E. AU - Kirik, O. V. PY - 2016 DA - 2016// TI - Brain microglia and microglial markers JO - Neurosci Behav Physiol VL - 46 UR - https://doi.org/10.1007/s11055-016-0231-z DO - 10.1007/s11055-016-0231-z ID - Korzhevskii2016 ER - TY - JOUR AU - Kuperstein, I. AU - Broersen, K. AU - Benilova, I. AU - Rozenski, J. AU - Jonckheere, W. AU - Debulpaep, M. PY - 2010 DA - 2010// TI - Neurotoxicity of Alzheimer’s disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio JO - EMBO J VL - 29 UR - https://doi.org/10.1038/emboj.2010.211 DO - 10.1038/emboj.2010.211 ID - Kuperstein2010 ER - TY - JOUR AU - Lashley, T. AU - Revesz, T. AU - Plant, G. AU - Bandopadhyay, R. AU - Lees, A. AU - Frangione, B. PY - 2008 DA - 2008// TI - Expression of BRI2 mRNA and protein in normal human brain and familial British dementia:its relevance to the pathogenesis of disease JO - Neuropathol Appl Neurobiol VL - 34 UR - https://doi.org/10.1111/j.1365-2990.2008.00935.x.Expression DO - 10.1111/j.1365-2990.2008.00935.x.Expression ID - Lashley2008 ER - TY - JOUR AU - Lashley, T. AU - Rohrer, J. D. AU - Bandopadhyay, R. AU - Fry, C. AU - Ahmed, Z. AU - Isaacs, A. M. PY - 2011 DA - 2011// TI - A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies JO - Brain VL - 134 UR - https://doi.org/10.1093/brain/awr160 DO - 10.1093/brain/awr160 ID - Lashley2011 ER - TY - JOUR AU - Lee, C. Y. D. AU - Landreth, G. E. PY - 2010 DA - 2010// TI - The role of microglia in amyloid clearance from the AD brain JO - J Neural Transm VL - 117 UR - https://doi.org/10.1007/s00702-010-0433-4 DO - 10.1007/s00702-010-0433-4 ID - Lee2010 ER - TY - JOUR AU - Lemere, C. A. AU - Blusztajn, J. K. AU - Yamaguchi, H. AU - Wisniewski, T. M. AU - Saido, T. C. AU - Selkoe, D. J. PY - 1996 DA - 1996// TI - Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation JO - Neurobiol Dis VL - 3 UR - https://doi.org/10.1006/nbdi.1996.0003 DO - 10.1006/nbdi.1996.0003 ID - Lemere1996 ER - TY - JOUR AU - Lodeiro, M. AU - Puerta, E. AU - Ismail, M. -. A. -. M. AU - Rodriguez-Rodriguez, P. AU - Rönnbäck, A. AU - Codita, A. PY - 2017 DA - 2017// TI - Aggregation of the Inflammatory S100A8 Precedes Aβ Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and Aβ Productions JO - J Gerontol A Biol Sci Med Sci VL - 72 UR - https://doi.org/10.1093/gerona/glw073 DO - 10.1093/gerona/glw073 ID - Lodeiro2017 ER - TY - JOUR AU - Mann, D. AU - JOnes, D. AU - South, P. AU - Snowden, J. AU - Neary, D. PY - 1992 DA - 1992// TI - Deposition of amyloid beta protein in non-Alzheimer dementias: evidence for a neuronal origin of parenchymal deposits of beta protein in neurodegenerative disease JO - Acta Neruopathol VL - 83 UR - https://doi.org/10.1007/BF00713534 DO - 10.1007/BF00713534 ID - Mann1992 ER - TY - JOUR AU - Matsuda, S. AU - Giliberto, L. AU - Matsuda, Y. AU - Davies, P. AU - McGowan, E. AU - Pickford, F. PY - 2005 DA - 2005// TI - The familial dementia BRI2 gene binds the alzheimer gene amyloid-β precursor protein and inhibits amyloid-β production JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.C500217200 DO - 10.1074/jbc.C500217200 ID - Matsuda2005 ER - TY - JOUR AU - Matsuda, S. AU - Giliberto, L. AU - Matsuda, Y. AU - McGowan, E. M. AU - D’Adamio, L. PY - 2008 DA - 2008// TI - BRI2 inhibits amyloid -peptide precursor protein processing by interfering with the docking of secretases to the substrate JO - J Neurosci VL - 28 UR - https://doi.org/10.1523/JNEUROSCI.2094-08.2008 DO - 10.1523/JNEUROSCI.2094-08.2008 ID - Matsuda2008 ER - TY - JOUR AU - McKeever, P. M. AU - Kim, T. AU - Hesketh, A. R. AU - MacNair, L. AU - Miletic, D. AU - Favrin, G. PY - 2017 DA - 2017// TI - Cholinergic neuron gene expression differences captured by translational profiling in a mouse model of Alzheimer’s disease. Neurobiol JO - Aging VL - 57 UR - https://doi.org/10.1016/j.neurobiolaging.2017.05.014 DO - 10.1016/j.neurobiolaging.2017.05.014 ID - McKeever2017 ER - TY - JOUR AU - Miao, J. AU - Ding, M. AU - Zhang, A. AU - Xiao, Z. AU - Qi, W. AU - Luo, N. PY - 2012 DA - 2012// TI - Pleiotrophin promotes microglia proliferation and secretion of neurotrophic factors by activating extracellular signal-regulated kinase 1/2 pathway JO - Neurosci. Res VL - 74 UR - https://doi.org/10.1016/j.neures.2012.09.001 DO - 10.1016/j.neures.2012.09.001 ID - Miao2012 ER - TY - JOUR AU - Mills, C. PY - 2012 DA - 2012// TI - M1 and M2 macrophages: oracles of health and disease JO - Crit Rev Immunol VL - 32 UR - https://doi.org/10.1615/CritRevImmunol.v32.i6.10 DO - 10.1615/CritRevImmunol.v32.i6.10 ID - Mills2012 ER - TY - JOUR AU - Montine, T. AU - Phelps, C. AU - Beach, T. AU - Bigio, E. AU - Cairns, N. AU - Dickson, D. PY - 2012 DA - 2012// TI - National Institute on Aging-Alzheimer’s association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach JO - Acta Neuropathol VL - 123 UR - https://doi.org/10.1007/s00401-011-0910-3.National DO - 10.1007/s00401-011-0910-3.National ID - Montine2012 ER - TY - JOUR AU - Niimura, M. AU - Isoo, N. AU - Takasugi, N. AU - Tsuruoka, M. AU - Ui-Tei, K. AU - Saigo, K. PY - 2005 DA - 2005// TI - Aph-1 contributes to the stabilization and trafficking of the ??-secretase complex through mechanisms involving intermolecular and intramolecular interactions JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M409829200 DO - 10.1074/jbc.M409829200 ID - Niimura2005 ER - TY - JOUR AU - Okada, H. AU - Zhang, W. AU - Peterhoff, C. AU - Hwang, J. C. AU - Nixon, R. A. AU - Ryu, S. H. PY - 2010 DA - 2010// TI - Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing JO - FASEB J VL - 24 UR - https://doi.org/10.1096/fj.09-146357 DO - 10.1096/fj.09-146357 ID - Okada2010 ER - TY - JOUR AU - Pappolla, M. A. AU - Omar, R. A. AU - Vinters, H. V. PY - 1991 DA - 1991// TI - Image analysis microspectroscopy shows that neurons participate in the genesis of a subset of early primitive (diffuse) senile plaques JO - AmJPathol VL - 139 ID - Pappolla1991 ER - TY - JOUR AU - Portelius, E. AU - Lashley, T. AU - Westerlund, A. AU - Persson, R. AU - Fox, N. C. AU - Blennow, K. PY - 2015 DA - 2015// TI - Brain amyloid-Beta fragment signatures in pathological ageing and Alzheimer’s disease by hybrid immunoprecipitation mass spectrometry JO - Neurodegener Dis VL - 15 UR - https://doi.org/10.1159/000369465 DO - 10.1159/000369465 ID - Portelius2015 ER - TY - JOUR AU - Probst, A. AU - Langui, D. AU - Ulrich, J. PY - 1991 DA - 1991// TI - Alzheimer’s disease: a description of the structural lesions JO - Brain Pathol VL - 1 UR - https://doi.org/10.1111/j.1750-3639.1991.tb00666.x DO - 10.1111/j.1750-3639.1991.tb00666.x ID - Probst1991 ER - TY - JOUR AU - Ransohoff, R. M. AU - Perry, V. H. PY - 2009 DA - 2009// TI - Microglial physiology: unique stimuli, specialized responses JO - Annu Rev Immunol VL - 27 UR - https://doi.org/10.1146/annurev.immunol.021908.132528 DO - 10.1146/annurev.immunol.021908.132528 ID - Ransohoff2009 ER - TY - STD TI - Ries M, Loiola R, Shah UN, Gentleman SM, Solito E, Sastre M (2016) The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide. J Neuroinflammation 13(1). https://doi.org/10.1186/s12974-016-0692-6 ID - ref59 ER - TY - JOUR AU - Rijal Upadhaya, A. AU - Kosterin, I. AU - Kumar, S. AU - Von Arnim, C. A. F. AU - Yamaguchi, H. AU - Fändrich, M. PY - 2014 DA - 2014// TI - Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer’s disease JO - Brain VL - 137 UR - https://doi.org/10.1093/brain/awt362 DO - 10.1093/brain/awt362 ID - Rijal Upadhaya2014 ER - TY - STD TI - Roher a E, Palmer KC, Yurewicz EC, Ball MJ, Greenberg BD. Morphological and biochemical analyses of amyloid plaque core proteins purified from Alzheimer disease brain tissue. J Neurochem 1993;61(5):1916–26. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8229002 UR - http://www.ncbi.nlm.nih.gov/pubmed/8229002 ID - ref61 ER - TY - JOUR AU - Rosenbaum, S. AU - Kreft, S. AU - Etich, J. AU - Frie, C. AU - Stermann, J. AU - Grskovic, I. PY - 2011 DA - 2011// TI - Identification of novel binding partners (annexins) for the cell death signal phosphatidylserine and definition of their recognition motif JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M110.193086 DO - 10.1074/jbc.M110.193086 ID - Rosenbaum2011 ER - TY - JOUR AU - Rostagno, A. AU - Tomidokoro, Y. AU - Lashley, T. AU - Ng, D. AU - Plant, G. AU - Holton, J. PY - 2005 DA - 2005// TI - Chromosome 13 dementias JO - Cell Mol Life Sci VL - 62 UR - https://doi.org/10.1007/s00018-005-5092-5 DO - 10.1007/s00018-005-5092-5 ID - Rostagno2005 ER - TY - JOUR AU - Russo, C. AU - Violani, E. AU - Salis, S. AU - Venezia, V. AU - Dolcini, V. AU - Damonte, G. PY - 2002 DA - 2002// TI - Pyroglutamate-modified amyloid β-peptides - AβN3(pE) - strongly affect cultured neuron and astrocyte survival JO - J Neurochem VL - 82 UR - https://doi.org/10.1046/j.1471-4159.2002.01107.x DO - 10.1046/j.1471-4159.2002.01107.x ID - Russo2002 ER - TY - JOUR AU - Schafer, D. AU - Stevens, B. PY - 2013 DA - 2013// TI - Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system JO - Curr Opin Neurobiol VL - 23 UR - https://doi.org/10.1016/j.immuni.2010.12.017.Two-stage DO - 10.1016/j.immuni.2010.12.017.Two-stage ID - Schafer2013 ER - TY - JOUR AU - Selkoe, D. J. AU - Wolfe, M. S. PY - 2007 DA - 2007// TI - Presenilin: running with scissors in the membrane JO - Cell VL - 131 UR - https://doi.org/10.1016/j.cell.2007.10.012 DO - 10.1016/j.cell.2007.10.012 ID - Selkoe2007 ER - TY - JOUR AU - Shirotani, K. AU - Edbauer, D. AU - Prokop, S. AU - Haass, C. AU - Steiner, H. PY - 2004 DA - 2004// TI - Identification of distinct γ-secretase complexes with different APH-1 variants JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M405768200 DO - 10.1074/jbc.M405768200 ID - Shirotani2004 ER - TY - STD TI - Sosna J, Philipp S, Albay RI, Reyes-Ruiz JM, Baglietto-Vargas D, LaFerla FM, et al. Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease. Mol. Neurodegener. Mol Neurodegener; 2018;13(1):1–11. doi:https://doi.org/10.1186/s13024-018-0244-x ID - ref68 ER - TY - JOUR AU - Streit, W. J. AU - Braak, H. AU - Xue, Q. -. S. AU - Bechmann, I. PY - 2009 DA - 2009// TI - Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease JO - Acta Neuropathol VL - 118 UR - https://doi.org/10.1007/s00401-009-0556-6 DO - 10.1007/s00401-009-0556-6 ID - Streit2009 ER - TY - STD TI - Sun Z, Xie Y, Chen Y, Yang Q, Quan Z, Dai R et al (2017) Rab21, a novel PS1 interactor, regulates γ-secretase activity via PS1 subcellular distribution. Mol Neurobiol:1–15. https://doi.org/10.1007/s12035-017-0606-3 ID - ref70 ER - TY - STD TI - Szaruga M, Veugelen S, Benurwar M, Lismont S, Sepulveda-Falla D, Lleo A, et al. Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease. J. Exp. Med. 2015;(Icd):jem.20150892-. doi:https://doi.org/10.1084/jem.20150892 ID - ref71 ER - TY - JOUR AU - Tanzi, R. E. AU - Bertram, L. PY - 2005 DA - 2005// TI - Twenty years of the Alzheimer’s disease amyloid hypothesis: a genetic perspective JO - Cell VL - 120 UR - https://doi.org/10.1016/j.cell.2005.02.008 DO - 10.1016/j.cell.2005.02.008 ID - Tanzi2005 ER - TY - JOUR AU - Tarasoff-conway, J. M. AU - Carare, R. O. AU - Osorio, R. S. AU - Glodzik, L. AU - Fieremans, E. AU - Axel, L. PY - 2015 DA - 2015// TI - Clearance systems in the brain—implications for Alzheimer disease JO - Nat Rev Neurol VL - 11 UR - https://doi.org/10.1038/nrneurol.2015.119.Clearance DO - 10.1038/nrneurol.2015.119.Clearance ID - Tarasoff-conway2015 ER - TY - JOUR AU - Thal, D. R. AU - Rüb, U. AU - Orantes, M. AU - Braak, H. PY - 2002 DA - 2002// TI - Phases of Aβ-deposition in the human brain and its relevance for the development of AD JO - Neurology VL - 58 UR - https://doi.org/10.1212/WNL.58.12.1791 DO - 10.1212/WNL.58.12.1791 ID - Thal2002 ER - TY - JOUR AU - Thal, D. R. AU - Rüb, U. AU - Schultz, C. AU - Sassin, I. AU - Ghebremedhin, E. AU - Del Tredici, K. PY - 2000 DA - 2000// TI - Sequence of Abeta -protein deposition in the human medial temporal lobe JO - J Neuropathol Exp Neurol VL - 59 UR - https://doi.org/10.1093/jnen/59.8.733 DO - 10.1093/jnen/59.8.733 ID - Thal2000 ER - TY - JOUR AU - Thinakaran, G. AU - Koo, E. H. PY - 2008 DA - 2008// TI - Amyloid precursor protein trafficking, processing, and function JO - J Biol Chem VL - 283 UR - https://doi.org/10.1074/jbc.R800019200 DO - 10.1074/jbc.R800019200 ID - Thinakaran2008 ER - TY - STD TI - Tomidokoro Y, Lashley T, Rostagno A, Neubert TA, Bojsen-Møller M, Braendgaard H et al (2005) Familial Danish dementia - co-existence of Danish and Alzheimer amyloid subunits (ADan and a beta) in the absence of compact plaques. J Biol Chem 280(44):36883–36894 Available from: https://www.ncbi.nlm.nih.gov/pubmed/16091362 UR - https://www.ncbi.nlm.nih.gov/pubmed/16091362 ID - ref77 ER - TY - JOUR AU - Ueno, M. AU - Fujita, Y. AU - Tanaka, T. AU - Nakamura, Y. AU - Kikuta, J. AU - Ishii, M. PY - 2013 DA - 2013// TI - Layer V cortical neurons require microglial support for survival during postnatal development JO - Nat Neurosci Nature Publishing Group VL - 16 UR - https://doi.org/10.1038/nn.3358 DO - 10.1038/nn.3358 ID - Ueno2013 ER - TY - JOUR AU - van Strien, N. M. AU - Cappaert, N. L. M. AU - Witter, M. P. PY - 2009 DA - 2009// TI - The anatomy of memory: an interactive overview of the parahippocampal-hippocampal network JO - Nat Rev Neurosci VL - 10 UR - https://doi.org/10.1038/nrn2614 DO - 10.1038/nrn2614 ID - van Strien2009 ER - TY - JOUR AU - Vidal, R. AU - Frangione, B. AU - Rostagno, A. AU - Mead, S. AU - Révész, T. AU - Plant, G. PY - 1999 DA - 1999// TI - A stop-codon mutation in the BRI gene associated with familial British dementia JO - Nature VL - 399 UR - https://doi.org/10.1038/21637 DO - 10.1038/21637 ID - Vidal1999 ER - TY - JOUR AU - Vidal, R. AU - Revesz, T. AU - Rostagno, A. AU - Kim, E. AU - Holton, J. L. AU - Bek, T. PY - 2000 DA - 2000// TI - A decamer duplication in the 3’ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred JO - Proc Natl Acad Sci U S A VL - 97 UR - https://doi.org/10.1073/pnas.080076097 DO - 10.1073/pnas.080076097 ID - Vidal2000 ER - TY - JOUR AU - Wang, P. AU - Joberty, G. AU - Buist, A. AU - Vanoosthuyse, A. AU - Stancu, I. -. C. AU - Vasconcelos, B. PY - 2017 DA - 2017// TI - Tau interactome mapping based identification of Otub1 as tau deubiquitinase involved in accumulation of pathological tau forms in vitro and in vivo JO - Acta Neuropathol VL - 133 UR - https://doi.org/10.1007/s00401-016-1663-9 DO - 10.1007/s00401-016-1663-9 ID - Wang2017 ER - TY - JOUR AU - Wirths, O. AU - Walter, S. AU - Kraus, I. AU - Klafki, H. W. AU - Stazi, M. AU - Oberstein, T. J. PY - 2017 DA - 2017// TI - N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models. Alzheimers. Res. Ther JO - Alzheimers Res Ther VL - 9 UR - https://doi.org/10.1186/s13195-017-0309-z DO - 10.1186/s13195-017-0309-z ID - Wirths2017 ER - TY - JOUR AU - Wisniewski, H. M. AU - Sadowski, M. AU - Jakubowska-Sadowska, K. AU - Tarnawski, M. AU - Weigiel, J. PY - 1998 DA - 1998// TI - Diffuse, Lake-like amyloid-Beta deposits in the Parvopyramidal layer of the Presubiculum in Alzheimer disease JO - J Neuropathol Exp Neurol VL - 57 UR - https://doi.org/10.1097/00005072-199807000-00004 DO - 10.1097/00005072-199807000-00004 ID - Wisniewski1998 ER - TY - JOUR AU - Wittnam, J. L. AU - Portelius, E. AU - Zetterberg, H. AU - Gustavsson, M. K. AU - Schilling, S. AU - Koch, B. PY - 2012 DA - 2012// TI - Pyroglutamate amyloid β(aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease JO - J Biol Chem VL - 287 UR - https://doi.org/10.1074/jbc.M111.308601 DO - 10.1074/jbc.M111.308601 ID - Wittnam2012 ER - TY - JOUR AU - Xue, J. AU - Dong, J. H. AU - Huang, G. D. AU - Qu, X. F. AU - Wu, G. AU - Dong, X. R. PY - 2014 DA - 2014// TI - NF-κB signaling modulates radiation-induced microglial activation JO - Oncol Rep VL - 31 UR - https://doi.org/10.3892/or.2014.3144 DO - 10.3892/or.2014.3144 ID - Xue2014 ER - TY - JOUR AU - Zhang, X. H. F. AU - Leslie, C. S. AU - Chasin, L. A. PY - 2005 DA - 2005// TI - Computational searches for splicing signals JO - Methods VL - 37 UR - https://doi.org/10.1016/j.ymeth.2005.07.011 DO - 10.1016/j.ymeth.2005.07.011 ID - Zhang2005 ER -