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Table 1 Selected demographic, genetic and neuropathological details for 56 individuals with Down syndrome

From: The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer’s disease in individuals with Down syndrome

Case ID# UKBBN ID# gender age karyotype APOE Thal Braak Allen CAA Thal CAA
1 na M 0.01 na na 0 0 0 0
2 na F 0.1 na na 0 0 0 0
3 na M 1.6 na na 0 0 0 0
4 na M 1.6 na na 0 0 0 0
5 na F 3 na na 0 0 0 0
6 na M 11 na na 0 0 0 0
7 na F 13 na na 0 0 0 0
8 BBN_2966 M 13 47XY21 3,3 1 0 0 0
9 na M 23 na na 0 0 0 0
10 na F 27 na na 1 0 0 0
11 na M 35 na na 2 0 0 0
12 na M 36 na na 5 II 0 0
13 BBN_2963 F 37 47XX21 3,4 5 I 0 0
14 na F 39 na na 2 b* 0 0
15 na M 42 na na 5 V 1 1
16 BBN_17186 F 47 na na 5 VI 3 2
17 BBN_17189 M 47 na na 5 III 1 1
18 BBN_17178 F 49 na 3,4 4 III 1 1
19 BBN_2981 M 50 47XY21 3,4 3 II 1 1
20 na F 50 na na 0 b* 0 0
21 na M 51 na na 5 VI 1 1
22 BBN_2968 M 53 47XY21 3,3 5 III 1 1
23 BBN_3356 F 53 na 3,4 5 VI 2 1
24 BBN_16954 M 54 na 2,4 5 VI 3 2
25 BBN_3365 M 55 na 3,4 5 VI 2 1
26 na M 55 na na 5 V 1 1
27 BBN_3438 F 56 na 3,3 5 VI 1 1
28 BBN_16273 F 56 na 3,4 5 VI 1 1
29 BBN_2978 M 57 47XY21 3,3 5 V 3 2
30 na M 57 na na 5 VI 1 1
31 BBN_3020 F 58 47XX21 3,3 5 V 1 1
32 BBN_3355 M 58 na 3,4 5 VI 3 2
33 BBN_3358 F 58 na 3,3 5 VI 2 1
34 BBN_3437 F 58 na 2,3 5 V 1 1
35 BBN_3353 M 59 na 2,3 5 VI 3 2
36 BBN_3363 M 59 na 3,3 5 VI 2 1
37 BBN_2990 M 60 47XY21 3,3 5 VI 2 1
38 BBN_3364 M 60 na 3,3 5 VI 2 1
39 na F 60 na na 5 0 0 0
40 na M 60 na na 5 VI 2 1
41 BBN_16835 M 60 na 3,3 5 III 2 1
42 BBN_3352 F 61 na 2,3 5 VI 3 2
43 BBN_3439 F 61 na 3,4 5 VI 2 1
44 BBN_2964 F 62 47XX21 3,3 5 V 3 2
45 BBN_2965 M 62 47XY21 3,3 5 V 1 1
46 BBN_2967 F 62 47XX21 3,3 5 IV 3 2
47 BBN_3354 M 62 na 3,3 5 VI 3 2
48 BBN_3441 M 62 na 2,3 5 VI 3 2
49 na M 63 na na 5 VI 1 1
50 BBN_2969 M 64 47XY21 3,3 5 IV 1 1
51 BBN_3440 F 64 na 3,3 5 VI 2 1
52 BBN_2975 M 65 47XY21 3,3 5 V 1 1
53 BBN_17004 M 65 na 3,3 5 V 1 1
54 na M 66 na na 5 V 1 1
55 na F 69 na na 5 VI 1 1
56 BBN_2985 M 76 47XY21 2,3 5 III 3 2
  1. Thal = Thal phase of amyloid deposition and Braak = Braak tau stage. CAA phenotype was assessed in accordance with Allen et al. (2014) and Thal et al. (2010). UKBBN = UK Brain Bank Network ID number, na = not available/applicable