Phosphorylation of different tau sites during progression of Alzheimer’s disease

Table 1 Individual case information. Demographic patient information

	Case	Age	Sex	Braakstage	Post mortem delay to fixation in hours	Fixation time in weeks	Clinical information	# on Western blot
Controls	1	68	M	0	54	7	Cognitively normal	1
	2	55	M	0	41	11	Cognitively normal	2
	3	70	M	0	72	6	Cognitively normal	–
	4	78	F	0	34	8	Cognitively normal	4
	5	73	M	0	25	9	Cognitively normal	–
	mean	68.8		0	45.2	8.2
Braak I/II Low	6	96	F	2	114	49	Mild dementia	6
	7	77	M	2	83	15	Cognitively normal	7
	8	94	F	2	15	9	Cognitively normal	–
	9	70	M	2	39	7	Multiple psychiatric and physical problems	9
	10	74	F	1	49	10	Cognitively normal	10
	mean	82.2		1.8	60	18
Braak III/IV Mod.	11	75	M	4	82	23	Cognitively normal	11
	12	79	M	3	13	15	Cognitively normal	12
	13	81	M	3	82	8	Unspecified dementia	13
	14	98	F	3	59	8	Cognitively normal	14
	15	91	M	3	48	9	Moderate cognitive impairment and vascular disease	15
	mean	84.8		3.2	56.8	12.6
Braak V/VI High	16	84	F	6	47	16	Severe dementia, anxiety and depression	–
	17	77	F	6	63	5	Dementia	17
	18	80	F	6	32	16	Dementia	18
	19	86	F	6	5	6	Dementia	19
	20	89	F	6	85	8	Dementia	–
	mean	83.2		6	46.4	10.2

ISSN: 2051-5960