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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias

Fig. 1

Tau immunohistochemistry in Alzheimer’s disease cases. af) Representative images from frontal cortex, showing macroscopic AT8 distribution in the Alzheimer’s disease cases AD1–AD4, the FTDP-17 case with a R406W MAPT mutation (FTDP1) and the control case CTRL4. gx) Typical microscopic AT8 positive neurofibrillary tau aggregates in frontal cortex, temporal cortex and hippocampus. Abbreviations: AD, Alzheimer’s disease; FTDP, frontotemporal dementia with parkinsonism linked to chromosome 17; CTRL, control; FC, frontal cortex; TC, temporal cortex; HP, hippocampus

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