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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Prion infectivity is encoded exclusively within the structure of proteinase K-resistant fragments of synthetically generated recombinant PrPSc

Fig. 4

The recombinant prion infectivity is encoded within its PK-resistant protein conformation. a Samples from the same batch of recPrPSc were treated with PK as indicated. The lane marked by * was loaded with 5 times of PK-resistant recPrPSc (1 mg/mL, 37 °C, 16 h). b The prion infectivity of samples in (a) as evaluated by the Elispot cell infection assay

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