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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease

Fig. 5

Inter-modular relationships and module expression profiles of AD-related modules. a Module eigenprotein meta-network showing the inter-modular relationships of the identified 24 protein co-expression modules. b Box plots showing module eigenprotein (ME) values in AD and control (CT) cases for modules that are positively correlated with AD phenotypes. c Box plots showing ME values in AD and CT cases for modules that are negatively correlated with AD phenotypes. Box plots depict the mean (horizontal bars) and variance (25th to 75th percentiles), and significance (P-value) of differential ME expression in AD versus control was determined using unpaired two-tailed Student’s t test

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