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Table 4 Area (nm2), perimeter (nm) and curvature (ratio) of the SAS. All data are corrected for shrinkage factor

From: Three-dimensional analysis of synapses in the transentorhinal cortex of Alzheimer’s disease patients

Group Type of synapse Area of SAS (nm2; mean ± sem) Perimeter of SAS (nm; mean ± sem) Curvature of SAS (mean ± sem)
Control AS 117,800 ± 1957 1653 ± 18.94 0.049 ± 0.001
SS 76,190 ± 4082 1423 ± 49.14 0.050 ± 0.004
Alzheimer AS 123,200 ± 2327 1697 ± 22.96 0.049 ± 0.001
SS 67,750 ± 3611 1284 ± 41.00 0.049 ± 0.003
  1. AS asymmetric synapses, sem standard error of the mean, SAS synaptic apposition surface, SS symmetric synapses
  2. The data for individual cases are shown in Additional file 1: Table S3