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Table 4 Gene expression validation of genes encoding transcription factors using ddPCR in the rat perilesional cortex, thalamus and hippocampus at three months after TBI

From: Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

 

Cebpd

Pax6

Spi1

Tp73

Perilesional cortex

 Fold change

2.58

1.64

1.75

6.67

 p-value

0.0003996

0.004795

0.007592

0.0007992

Thalamus

 Fold change

1.55

1.13

1.65

0.55

 p-value

0.2721

0.4559

0.06633

0.3884

Hippocampus

 Fold change

0.74

0.91

1.00

0.79

 p-value

0.1375

0.7308

0.6282

0.6282

  1. Statistical significances: Fold change and corresponding p-value (< 0.05) are shown in bolded font