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Table 4 Gene expression validation of genes encoding transcription factors using ddPCR in the rat perilesional cortex, thalamus and hippocampus at three months after TBI

From: Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

  Cebpd Pax6 Spi1 Tp73
Perilesional cortex
 Fold change 2.58 1.64 1.75 6.67
 p-value 0.0003996 0.004795 0.007592 0.0007992
Thalamus
 Fold change 1.55 1.13 1.65 0.55
 p-value 0.2721 0.4559 0.06633 0.3884
Hippocampus
 Fold change 0.74 0.91 1.00 0.79
 p-value 0.1375 0.7308 0.6282 0.6282
  1. Statistical significances: Fold change and corresponding p-value (< 0.05) are shown in bolded font