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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

Fig. 3

SignaLink transcription regulatory network (TRN) of Tp73 and its targets in the perilesional cortex. SignaLink network analysis revealed 54 targets, of which five were upregulated and 11 were downregulated in the perilesional cortex 3 months post-TBI. Color codes: blue circle, downregulation after TBI; yellow circle, upregulation after TBI; white circle, no change in gene expression after TBI; green line, transcriptional interaction with Tp73; black line, inter-target interaction

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