TY - JOUR AU - Ahmadian, S. S. AU - Rezvanian, A. AU - Peterson, M. AU - Weintraub, S. AU - Bigio, E. H. AU - Mesulam, M. M. AU - Geula, C. PY - 2015 DA - 2015// TI - Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease JO - Neurobiol Aging VL - 36 UR - https://doi.org/10.1016/j.neurobiolaging.2015.09.001 DO - 10.1016/j.neurobiolaging.2015.09.001 ID - Ahmadian2015 ER - TY - JOUR AU - Altundag, A. AU - Ay, S. A. AU - Hira, S. AU - Salihoglu, M. AU - Baskoy, K. AU - Deniz, F. AU - Tekeli, H. AU - Kurt, O. AU - Yonem, A. AU - Hummel, T. PY - 2017 DA - 2017// TI - Olfactory and gustatory functions in patients with non-complicated type 1 diabetes mellitus JO - Eur Arch Otorhinolaryngol VL - 274 UR - https://doi.org/10.1007/s00405-017-4497-8 DO - 10.1007/s00405-017-4497-8 ID - Altundag2017 ER - TY - JOUR AU - Bachor, T. P. AU - Karbanova, J. AU - Buttner, E. AU - Bermudez, V. AU - Marquioni-Ramella, M. AU - Carmeliet, P. AU - Corbeil, D. AU - Suburo, A. M. PY - 2017 DA - 2017// TI - Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes JO - Neurobiol Dis VL - 108 UR - https://doi.org/10.1016/j.nbd.2017.07.010 DO - 10.1016/j.nbd.2017.07.010 ID - Bachor2017 ER - TY - STD TI - Baskin DG, Stein LJ, Ikeda H, Woods SC, Figlewicz DP, Porte D, Jr., Greenwood MR, Dorsa DM (1985) Genetically obese Zucker rats have abnormally low brain insulin content. Life Sci 36: 627–633 ID - ref4 ER - TY - JOUR AU - Bekkers, J. M. AU - Suzuki, N. PY - 2013 DA - 2013// TI - Neurons and circuits for odor processing in the piriform cortex JO - Trends Neurosci VL - 36 UR - https://doi.org/10.1016/j.tins.2013.04.005 DO - 10.1016/j.tins.2013.04.005 ID - Bekkers2013 ER - TY - JOUR AU - Biessels, G. J. AU - Reagan, L. P. PY - 2015 DA - 2015// TI - Hippocampal insulin resistance and cognitive dysfunction JO - Nat Rev Neurosci VL - 16 UR - https://doi.org/10.1038/nrn4019 DO - 10.1038/nrn4019 ID - Biessels2015 ER - TY - JOUR AU - Bonfanti, L. AU - Olive, S. AU - Poulain, D. A. AU - Theodosis, D. T. PY - 1992 DA - 1992// TI - Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: an immunohistochemical study JO - Neuroscience VL - 49 UR - https://doi.org/10.1016/0306-4522(92)90107-D DO - 10.1016/0306-4522(92)90107-D ID - Bonfanti1992 ER - TY - JOUR AU - Brady, D. R. AU - Mufson, E. J. PY - 1997 DA - 1997// TI - Parvalbumin-immunoreactive neurons in the hippocampal formation of Alzheimer's diseased brain JO - Neuroscience VL - 80 UR - https://doi.org/10.1016/S0306-4522(97)00068-7 DO - 10.1016/S0306-4522(97)00068-7 ID - Brady1997 ER - TY - JOUR AU - Bramerson, A. AU - Johansson, L. AU - Ek, L. AU - Nordin, S. AU - Bende, M. PY - 2004 DA - 2004// TI - Prevalence of olfactory dysfunction: the skovde population-based study JO - Laryngoscope VL - 114 UR - https://doi.org/10.1097/00005537-200404000-00026 DO - 10.1097/00005537-200404000-00026 ID - Bramerson2004 ER - TY - STD TI - Candeias E, Sebastiao I, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI, Duarte AI (2017) Brain GLP-1/IGF-1 signaling and autophagy mediate Exendin-4 protection against apoptosis in type 2 diabetic rats. Mol Neurobiol. https://doi.org/10.1007/s12035-017-0622-3 ID - ref10 ER - TY - JOUR AU - Cardin, J. A. AU - Carlen, M. AU - Meletis, K. AU - Knoblich, U. AU - Zhang, F. AU - Deisseroth, K. AU - Tsai, L. H. AU - Moore, C. I. PY - 2009 DA - 2009// TI - Driving fast-spiking cells induces gamma rhythm and controls sensory responses JO - Nature VL - 459 UR - https://doi.org/10.1038/nature08002 DO - 10.1038/nature08002 ID - Cardin2009 ER - TY - JOUR AU - Cassano, T. AU - Romano, A. AU - Macheda, T. AU - Colangeli, R. AU - Cimmino, C. S. AU - Petrella, A. AU - LaFerla, F. M. AU - Cuomo, V. AU - Gaetani, S. PY - 2011 DA - 2011// TI - Olfactory memory is impaired in a triple transgenic model of Alzheimer disease JO - Behav Brain Res VL - 224 UR - https://doi.org/10.1016/j.bbr.2011.06.029 DO - 10.1016/j.bbr.2011.06.029 ID - Cassano2011 ER - TY - JOUR AU - Coronas-Samano, G. AU - Baker, K. L. AU - Tan, W. J. AU - Ivanova, A. V. AU - Verhagen, J. V. PY - 2016 DA - 2016// TI - Fus1 KO mouse as a model of oxidative stress-mediated sporadic Alzheimer's disease: circadian disruption and long-term spatial and olfactory memory impairments JO - Front Aging Neurosci VL - 8 UR - https://doi.org/10.3389/fnagi.2016.00268 DO - 10.3389/fnagi.2016.00268 ID - Coronas-Samano2016 ER - TY - JOUR AU - Cukierman, T. AU - Gerstein, H. C. AU - Williamson, J. D. PY - 2005 DA - 2005// TI - Cognitive decline and dementia in diabetes--systematic overview of prospective observational studies JO - Diabetologia VL - 48 UR - https://doi.org/10.1007/s00125-005-0023-4 DO - 10.1007/s00125-005-0023-4 ID - Cukierman2005 ER - TY - JOUR AU - D'Amico, M. AU - Di Filippo, C. AU - Marfella, R. AU - Abbatecola, A. M. AU - Ferraraccio, F. AU - Rossi, F. AU - Paolisso, G. PY - 2010 DA - 2010// TI - Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice JO - Exp Gerontol VL - 45 UR - https://doi.org/10.1016/j.exger.2009.12.004 DO - 10.1016/j.exger.2009.12.004 ID - D'Amico2010 ER - TY - STD TI - Darsalia V, Larsson M, Lietzau G, Nathanson D, Nystrom T, Klein T, Patrone C (2016) Gliptins-mediated neuroprotection against stroke requires chronic pre-treatment and is glucagon-like peptide-1 receptor independent. Diabetes Obes Metab. https://doi.org/10.1111/dom.12641 ID - ref16 ER - TY - JOUR AU - Darsalia, V. AU - Ortsater, H. AU - Olverling, A. AU - Darlof, E. AU - Wolbert, P. AU - Nystrom, T. AU - Klein, T. AU - Sjoholm, A. AU - Patrone, C. PY - 2013 DA - 2013// TI - The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride JO - Diabetes VL - 62 UR - https://doi.org/10.2337/db12-0988 DO - 10.2337/db12-0988 ID - Darsalia2013 ER - TY - JOUR AU - Daulatzai, M. A. PY - 2015 DA - 2015// TI - Olfactory dysfunction: its early temporal relationship and neural correlates in the pathogenesis of Alzheimer's disease JO - J Neural Transm (Vienna) VL - 122 UR - https://doi.org/10.1007/s00702-015-1404-6 DO - 10.1007/s00702-015-1404-6 ID - Daulatzai2015 ER - TY - JOUR AU - Deacon, C. F. AU - Holst, J. J. PY - 2013 DA - 2013// TI - Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety JO - Expert Opin Pharmacother VL - 14 UR - https://doi.org/10.1517/14656566.2013.824966 DO - 10.1517/14656566.2013.824966 ID - Deacon2013 ER - TY - JOUR AU - Doty, R. L. PY - 2017 DA - 2017// TI - Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate? JO - Lancet Neurol VL - 16 UR - https://doi.org/10.1016/S1474-4422(17)30123-0 DO - 10.1016/S1474-4422(17)30123-0 ID - Doty2017 ER - TY - JOUR AU - Franks, K. H. AU - Chuah, M. I. AU - King, A. E. AU - Vickers, J. C. PY - 2015 DA - 2015// TI - Connectivity of pathology: the olfactory system as a model for network-driven mechanisms of Alzheimer's disease pathogenesis JO - Front Aging Neurosci VL - 7 UR - https://doi.org/10.3389/fnagi.2015.00234 DO - 10.3389/fnagi.2015.00234 ID - Franks2015 ER - TY - STD TI - Gault VA, Lennox R, Flatt PR (2015) Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline. Diabetes Obes Metab. https://doi.org/10.1111/dom.12432 ID - ref22 ER - TY - JOUR AU - Giger, R. AU - Nicoucar, K. AU - Kurt, A. M. AU - Grouzman, E. AU - Lacroix, J. S. PY - 2000 DA - 2000// TI - Study of the enzyme peptidyl peptidase IV in nasal mucosa JO - Schweiz Med Wochenschr Suppl VL - 125 ID - Giger2000 ER - TY - JOUR AU - Gilbert, P. E. AU - Murphy, C. PY - 2004 DA - 2004// TI - The effect of the ApoE epsilon4 allele on recognition memory for olfactory and visual stimuli in patients with pathologically confirmed Alzheimer's disease, probable Alzheimer's disease, and healthy elderly controls JO - J Clin Exp Neuropsychol VL - 26 UR - https://doi.org/10.1080/13803390490509439 DO - 10.1080/13803390490509439 ID - Gilbert2004 ER - TY - JOUR AU - Gottfried, J. A. PY - 2010 DA - 2010// TI - Central mechanisms of odour object perception JO - Nat Rev Neurosci VL - 11 UR - https://doi.org/10.1038/nrn2883 DO - 10.1038/nrn2883 ID - Gottfried2010 ER - TY - JOUR AU - Gouveri, E. AU - Katotomichelakis, M. AU - Gouveris, H. AU - Danielides, V. AU - Maltezos, E. AU - Papanas, N. PY - 2014 DA - 2014// TI - Olfactory dysfunction in type 2 diabetes mellitus: an additional manifestation of microvascular disease? JO - Angiology VL - 65 UR - https://doi.org/10.1177/0003319714520956 DO - 10.1177/0003319714520956 ID - Gouveri2014 ER - TY - JOUR AU - Groeneveld, O. N. AU - Kappelle, L. J. AU - Biessels, G. J. PY - 2016 DA - 2016// TI - Potentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitus JO - J Diabetes Invest VL - 7 UR - https://doi.org/10.1111/jdi.12420 DO - 10.1111/jdi.12420 ID - Groeneveld2016 ER - TY - JOUR AU - Gundersen, H. J. AU - Bagger, P. AU - Bendtsen, T. F. AU - Evans, S. M. AU - Korbo, L. AU - Marcussen, N. AU - Moller, A. AU - Nielsen, K. AU - Nyengaard, J. R. AU - Pakkenberg, B. PY - 1988 DA - 1988// TI - The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis JO - APMIS VL - 96 UR - https://doi.org/10.1111/j.1699-0463.1988.tb00954.x DO - 10.1111/j.1699-0463.1988.tb00954.x ID - Gundersen1988 ER - TY - JOUR AU - Hamilton, L. K. AU - Aumont, A. AU - Julien, C. AU - Vadnais, A. AU - Calon, F. AU - Fernandes, K. J. PY - 2010 DA - 2010// TI - Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease JO - Eur J Neurosci VL - 32 UR - https://doi.org/10.1111/j.1460-9568.2010.07379.x DO - 10.1111/j.1460-9568.2010.07379.x ID - Hamilton2010 ER - TY - JOUR AU - Hardigan, T. AU - Yasir, A. AU - Abdelsaid, M. AU - Coucha, M. AU - El-Shaffey, S. AU - Li, W. AU - Johnson, M. H. AU - Ergul, A. PY - 2016 DA - 2016// TI - Linagliptin treatment improves cerebrovascular function and remodeling and restores reduced cerebral perfusion in type 2 diabetes JO - Am J Physiol Regul Integr Comp Physiol VL - 311 UR - https://doi.org/10.1152/ajpregu.00057.2016 DO - 10.1152/ajpregu.00057.2016 ID - Hardigan2016 ER - TY - JOUR AU - Hardy, D. AU - Saghatelyan, A. PY - 2017 DA - 2017// TI - Different forms of structural plasticity in the adult olfactory bulb JO - Neurogenesis (Austin) VL - 4 UR - https://doi.org/10.1080/23262133.2017.1301850 DO - 10.1080/23262133.2017.1301850 ID - Hardy2017 ER - TY - JOUR AU - Hof, P. R. AU - Morrison, J. H. PY - 1991 DA - 1991// TI - Neocortical neuronal subpopulations labeled by a monoclonal antibody to calbindin exhibit differential vulnerability in Alzheimer's disease JO - Exp Neurol VL - 111 UR - https://doi.org/10.1016/0014-4886(91)90096-U DO - 10.1016/0014-4886(91)90096-U ID - Hof1991 ER - TY - STD TI - Hussain S, Mansouri S, Sjoholm A, Patrone C, Darsalia V (2014) Evidence for cortical neuronal loss in male type 2 diabetic Goto-Kakizaki rats. JAD. https://doi.org/10.3233/JAD-131958 ID - ref33 ER - TY - JOUR AU - Ichimiya, Y. AU - Emson, P. C. AU - Mountjoy, C. Q. AU - Lawson, D. E. AU - Heizmann, C. W. PY - 1988 DA - 1988// TI - Loss of calbindin-28K immunoreactive neurones from the cortex in Alzheimer-type dementia JO - Brain Res VL - 475 UR - https://doi.org/10.1016/0006-8993(88)90210-7 DO - 10.1016/0006-8993(88)90210-7 ID - Ichimiya1988 ER - TY - JOUR AU - Inaguma, Y. AU - Shinohara, H. AU - Inagaki, T. AU - Kato, K. PY - 1992 DA - 1992// TI - Immunoreactive parvalbumin concentrations in parahippocampal gyrus decrease in patients with Alzheimer's disease JO - J Neurol Sci VL - 110 UR - https://doi.org/10.1016/0022-510X(92)90009-A DO - 10.1016/0022-510X(92)90009-A ID - Inaguma1992 ER - TY - JOUR AU - Isaacson, J. S. PY - 2010 DA - 2010// TI - Odor representations in mammalian cortical circuits JO - Curr Opin Neurobiol VL - 20 UR - https://doi.org/10.1016/j.conb.2010.02.004 DO - 10.1016/j.conb.2010.02.004 ID - Isaacson2010 ER - TY - JOUR AU - Isik, A. T. AU - Soysal, P. AU - Yay, A. AU - Usarel, C. PY - 2017 DA - 2017// TI - The effects of sitagliptin, a DPP-4 inhibitor, on cognitive functions in elderly diabetic patients with or without Alzheimer's disease JO - Diabetes Res Clin Pract VL - 123 UR - https://doi.org/10.1016/j.diabres.2016.12.010 DO - 10.1016/j.diabres.2016.12.010 ID - Isik2017 ER - TY - JOUR AU - Jan, Y. N. AU - Jan, L. Y. PY - 2010 DA - 2010// TI - Branching out: mechanisms of dendritic arborization JO - Nat Rev Neurosci VL - 11 UR - https://doi.org/10.1038/nrn2836 DO - 10.1038/nrn2836 ID - Jan2010 ER - TY - JOUR AU - Jorgensen, M. B. AU - Buch, N. H. PY - 1961 DA - 1961// TI - Studies on the sense of smell and taste in diabetics JO - Acta Otolaryngol VL - 53 UR - https://doi.org/10.3109/00016486109126521 DO - 10.3109/00016486109126521 ID - Jorgensen1961 ER - TY - JOUR AU - Kalaria, R. N. PY - 2009 DA - 2009// TI - Neurodegenerative disease: diabetes, microvascular pathology and Alzheimer disease. Nature reviews JO - Neurology VL - 5 ID - Kalaria2009 ER - TY - JOUR AU - Klempin, F. AU - Kronenberg, G. AU - Cheung, G. AU - Kettenmann, H. AU - Kempermann, G. PY - 2011 DA - 2011// TI - Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0025760 DO - 10.1371/journal.pone.0025760 ID - Klempin2011 ER - TY - JOUR AU - Kodl, C. T. AU - Seaquist, E. R. PY - 2008 DA - 2008// TI - Cognitive dysfunction and diabetes mellitus JO - Endocr Rev VL - 29 UR - https://doi.org/10.1210/er.2007-0034 DO - 10.1210/er.2007-0034 ID - Kodl2008 ER - TY - JOUR AU - Kook, S. Y. AU - Jeong, H. AU - Kang, M. J. AU - Park, R. AU - Shin, H. J. AU - Han, S. H. AU - Son, S. M. AU - Song, H. AU - Baik, S. H. AU - Moon, M. PY - 2014 DA - 2014// TI - Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model JO - Cell Death Differ VL - 21 UR - https://doi.org/10.1038/cdd.2014.67 DO - 10.1038/cdd.2014.67 ID - Kook2014 ER - TY - JOUR AU - Kornelius, E. AU - Lin, C. L. AU - Chang, H. H. AU - Li, H. H. AU - Huang, W. N. AU - Yang, Y. S. AU - Lu, Y. L. AU - Peng, C. H. AU - Huang, C. N. PY - 2015 DA - 2015// TI - DPP-4 inhibitor Linagliptin attenuates Abeta-induced cytotoxicity through activation of AMPK in neuronal cells JO - CNS Neurosci Ther VL - 21 UR - https://doi.org/10.1111/cns.12404 DO - 10.1111/cns.12404 ID - Kornelius2015 ER - TY - JOUR AU - Kosaraju, J. AU - Gali, C. C. AU - Khatwal, R. B. AU - Dubala, A. AU - Chinni, S. AU - Holsinger, R. M. AU - Madhunapantula, V. S. AU - Muthureddy Nataraj, S. K. AU - Basavan, D. PY - 2013 DA - 2013// TI - Saxagliptin: a dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease JO - Neuropharmacology VL - 72 UR - https://doi.org/10.1016/j.neuropharm.2013.04.008 DO - 10.1016/j.neuropharm.2013.04.008 ID - Kosaraju2013 ER - TY - STD TI - Kosaraju J, Holsinger RM, Guo L, Tam KY (2016) Linagliptin, a dipeptidyl Peptidase-4 inhibitor, mitigates cognitive deficits and pathology in the 3xTg-AD mouse model of Alzheimer's disease. Mol Neurobio. https://doi.org/10.1007/s12035-016-0125-7 ID - ref46 ER - TY - JOUR AU - Kosaraju, J. AU - Madhunapantula, S. V. AU - Chinni, S. AU - Khatwal, R. B. AU - Dubala, A. AU - Muthureddy Nataraj, S. K. AU - Basavan, D. PY - 2014 DA - 2014// TI - Dipeptidyl peptidase-4 inhibition by Pterocarpus Marsupium and Eugenia Jambolana ameliorates streptozotocin induced Alzheimer's disease JO - Behav Brain Res VL - 267 UR - https://doi.org/10.1016/j.bbr.2014.03.026 DO - 10.1016/j.bbr.2014.03.026 ID - Kosaraju2014 ER - TY - JOUR AU - Lacroix, M. C. AU - Caillol, M. AU - Durieux, D. AU - Monnerie, R. AU - Grebert, D. AU - Pellerin, L. AU - Repond, C. AU - Tolle, V. AU - Zizzari, P. AU - Baly, C. PY - 2015 DA - 2015// TI - Long-lasting metabolic imbalance related to obesity alters olfactory tissue homeostasis and impairs olfactory-driven behaviors JO - Chem Senses VL - 40 UR - https://doi.org/10.1093/chemse/bjv039 DO - 10.1093/chemse/bjv039 ID - Lacroix2015 ER - TY - JOUR AU - Lang, B. T. AU - Yan, Y. AU - Dempsey, R. J. AU - Vemuganti, R. PY - 2009 DA - 2009// TI - Impaired neurogenesis in adult type-2 diabetic rats JO - Brain Res VL - 1258 UR - https://doi.org/10.1016/j.brainres.2008.12.026 DO - 10.1016/j.brainres.2008.12.026 ID - Lang2009 ER - TY - JOUR AU - Larsson, M. AU - Hedner, M. AU - Papenberg, G. AU - Seubert, J. AU - Backman, L. AU - Laukka, E. J. PY - 2016 DA - 2016// TI - Olfactory memory in the old and very old: relations to episodic and semantic memory and APOE genotype JO - Neurobiol Aging VL - 38 UR - https://doi.org/10.1016/j.neurobiolaging.2015.11.012 DO - 10.1016/j.neurobiolaging.2015.11.012 ID - Larsson2016 ER - TY - JOUR AU - Le Floch, J. P. AU - Le Lievre, G. AU - Labroue, M. AU - Paul, M. AU - Peynegre, R. AU - Perlemuter, L. PY - 1993 DA - 1993// TI - Smell dysfunction and related factors in diabetic patients JO - Diabetes Care VL - 16 UR - https://doi.org/10.2337/diacare.16.6.934 DO - 10.2337/diacare.16.6.934 ID - Le Floch1993 ER - TY - STD TI - Lehmkuhl AM, Dirr ER, Fleming SM (2014) Olfactory assays for mouse models of neurodegenerative disease. JOVE:e51804. https://doi.org/10.3791/51804 ID - ref52 ER - TY - JOUR AU - Li, W. AU - Howard, J. D. AU - Gottfried, J. A. PY - 2010 DA - 2010// TI - Disruption of odour quality coding in piriform cortex mediates olfactory deficits in Alzheimer's disease JO - Brain J Neurol VL - 133 UR - https://doi.org/10.1093/brain/awq209 DO - 10.1093/brain/awq209 ID - Li2010 ER - TY - JOUR AU - Li, X. H. AU - Xin, X. AU - Wang, Y. AU - Wu, J. Z. AU - Jin, Z. D. AU - Ma, L. N. AU - Nie, C. J. AU - Xiao, X. AU - Hu, Y. AU - Jin, M. W. PY - 2013 DA - 2013// TI - Pentamethylquercetin protects against diabetes-related cognitive deficits in diabetic Goto-Kakizaki rats JO - JAD VL - 34 ID - Li2013 ER - TY - JOUR AU - Lietzau, G. AU - Darsalia, V. AU - Pintana, H. AU - Ostenson, C. G. AU - Nystrom, T. AU - Fisahn, A. AU - Patrone, C. PY - 2017 DA - 2017// TI - Type 2 diabetes alters hippocampal gamma oscillations: a potential mechanism behind impaired cognition JO - Psychoneuroendocrinology VL - 82 UR - https://doi.org/10.1016/j.psyneuen.2017.04.012 DO - 10.1016/j.psyneuen.2017.04.012 ID - Lietzau2017 ER - TY - STD TI - Lietzau G, Nystrom T, Ostenson CG, Darsalia V, Patrone C (2016) Type 2 diabetes-induced neuronal pathology in the piriform cortex of the rat is reversed by the GLP-1 receptor agonist Exendin-4. Oncotarget. https://doi.org/10.18632/oncotarget.6823 ID - ref56 ER - TY - JOUR AU - Livingston, J. N. AU - Unger, J. W. AU - Moxley, R. T. AU - Moss, A. PY - 1993 DA - 1993// TI - Phosphotyrosine-containing proteins in the CNS of obese Zucker rats are decreased in the absence of changes in the insulin receptor JO - Neuroendocrinology VL - 57 UR - https://doi.org/10.1159/000126395 DO - 10.1159/000126395 ID - Livingston1993 ER - TY - JOUR AU - Luitse, M. J. AU - Biessels, G. J. AU - Rutten, G. E. AU - Kappelle, L. J. PY - 2012 DA - 2012// TI - Diabetes, hyperglycaemia, and acute ischaemic stroke JO - Lancet Neurol VL - 11 UR - https://doi.org/10.1016/S1474-4422(12)70005-4 DO - 10.1016/S1474-4422(12)70005-4 ID - Luitse2012 ER - TY - JOUR AU - Mansouri, S. AU - Barde, S. AU - Ortsater, H. AU - Eweida, M. AU - Darsalia, V. AU - Langel, U. AU - Sjoholm, A. AU - Hokfelt, T. AU - Patrone, C. PY - 2013 DA - 2013// TI - GalR3 activation promotes adult neural stem cell survival in response to a diabetic milieu JO - J Neurochem VL - 127 UR - https://doi.org/10.1111/jnc.12396 DO - 10.1111/jnc.12396 ID - Mansouri2013 ER - TY - STD TI - Mansouri S, Ortsater H, Pintor Gallego O, Darsalia V, Sjoholm A, Patrone C (2011) Pituitary adenylate cyclase-activating polypeptide counteracts the impaired adult neural stem cell viability induced by palmitate. J Neurosci Res. https://doi.org/10.1002/jnr.22803 ID - ref60 ER - TY - STD TI - Markopoulou K, Chase BA, Robowski P, Strongosky A, Narozanska E, Sitek EJ, Berdynski M, Barcikowska M, Baker MC, Rademakers Ret al (2016) Assessment of olfactory function in MAPT-associated neurodegenerative disease reveals odor-identification irreproducibility as a non-disease-specific, general characteristic of olfactory dysfunction. PLoS One 11: e0165112 https://doi.org/10.1371/journal.pone.0165112 ID - ref61 ER - TY - JOUR AU - Matsunaga, Y. AU - Negishi, T. AU - Hatakeyama, A. AU - Kawagoe, Y. AU - Sawano, E. AU - Tashiro, T. PY - 2016 DA - 2016// TI - Impairment of synaptic development in the hippocampus of diabetic Goto-Kakizaki rats JO - Int J Dev Neurosci VL - 53 UR - https://doi.org/10.1016/j.ijdevneu.2016.07.004 DO - 10.1016/j.ijdevneu.2016.07.004 ID - Matsunaga2016 ER - TY - JOUR AU - Moreira, P. I. AU - Santos, M. S. AU - Moreno, A. M. AU - Seica, R. AU - Oliveira, C. R. PY - 2003 DA - 2003// TI - Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure JO - Diabetes VL - 52 UR - https://doi.org/10.2337/diabetes.52.6.1449 DO - 10.2337/diabetes.52.6.1449 ID - Moreira2003 ER - TY - JOUR AU - Moreira, T. AU - Malec, E. AU - Ostenson, C. G. AU - Efendic, S. AU - Liljequist, S. PY - 2007 DA - 2007// TI - Diabetic type II Goto-Kakizaki rats show progressively decreasing exploratory activity and learning impairments in fixed and progressive ratios of a lever-press task JO - Behav Brain Res VL - 180 UR - https://doi.org/10.1016/j.bbr.2007.02.034 DO - 10.1016/j.bbr.2007.02.034 ID - Moreira2007 ER - TY - JOUR AU - Murakawa, Y. AU - Zhang, W. AU - Pierson, C. R. AU - Brismar, T. AU - Ostenson, C. G. AU - Efendic, S. AU - Sima, A. A. PY - 2002 DA - 2002// TI - Impaired glucose tolerance and insulinopenia in the GK-rat causes peripheral neuropathy JO - Diabetes Metab Res Rev VL - 18 UR - https://doi.org/10.1002/dmrr.326 DO - 10.1002/dmrr.326 ID - Murakawa2002 ER - TY - JOUR AU - Nacher, J. AU - Bonfanti, L. PY - 2015 DA - 2015// TI - New neurons from old beliefs in the adult piriform cortex? A commentary on: occurrence of new neurons in the piriform cortex JO - Front Neuroanat VL - 9 UR - https://doi.org/10.3389/fnana.2015.00062 DO - 10.3389/fnana.2015.00062 ID - Nacher2015 ER - TY - JOUR AU - Nagayama, S. AU - Homma, R. AU - Imamura, F. PY - 2014 DA - 2014// TI - Neuronal organization of olfactory bulb circuits JO - Front Neural Circuits VL - 8 UR - https://doi.org/10.3389/fncir.2014.00098 DO - 10.3389/fncir.2014.00098 ID - Nagayama2014 ER - TY - JOUR AU - Naka, A. AU - Riedl, M. AU - Luger, A. AU - Hummel, T. AU - Mueller, C. A. PY - 2010 DA - 2010// TI - Clinical significance of smell and taste disorders in patients with diabetes mellitus JO - Eur Arch Otorhinolaryngol VL - 267 UR - https://doi.org/10.1007/s00405-009-1123-4 DO - 10.1007/s00405-009-1123-4 ID - Naka2010 ER - TY - JOUR AU - Ostenson, C. G. AU - Efendic, S. PY - 2007 DA - 2007// TI - Islet gene expression and function in type 2 diabetes; studies in the Goto-Kakizaki rat and humans JO - Diabetes Obes Metab VL - 9 UR - https://doi.org/10.1111/j.1463-1326.2007.00787.x DO - 10.1111/j.1463-1326.2007.00787.x ID - Ostenson2007 ER - TY - JOUR AU - Patrone, C. AU - Eriksson, O. AU - Lindholm, D. PY - 2014 DA - 2014// TI - Diabetes drugs and neurological disorders: new views and therapeutic possibilities JO - Lancet Diabetes Endocrinol VL - 2 UR - https://doi.org/10.1016/S2213-8587(13)70125-6 DO - 10.1016/S2213-8587(13)70125-6 ID - Patrone2014 ER - TY - JOUR AU - Patterson, D. S. AU - Turner, P. AU - Smart, J. V. PY - 1966 DA - 1966// TI - Smell threshold in diabetes mellitus JO - Nature VL - 209 UR - https://doi.org/10.1038/209625a0 DO - 10.1038/209625a0 ID - Patterson1966 ER - TY - JOUR AU - Poo, C. AU - Isaacson, J. S. PY - 2009 DA - 2009// TI - Odor representations in olfactory cortex: "sparse" coding, global inhibition, and oscillations JO - Neuron VL - 62 UR - https://doi.org/10.1016/j.neuron.2009.05.022 DO - 10.1016/j.neuron.2009.05.022 ID - Poo2009 ER - TY - JOUR AU - Portha, B. AU - Giroix, M. H. AU - Tourrel-Cuzin, C. AU - Le-Stunff, H. AU - Movassat, J. PY - 2012 DA - 2012// TI - The GK rat: a prototype for the study of non-overweight type 2 diabetes JO - Methods Mol Biol VL - 933 ID - Portha2012 ER - TY - JOUR AU - Riviere, S. AU - Soubeyre, V. AU - Jarriault, D. AU - Molinas, A. AU - Leger-Charnay, E. AU - Desmoulins, L. AU - Grebert, D. AU - Meunier, N. AU - Grosmaitre, X. PY - 2016 DA - 2016// TI - High fructose diet inducing diabetes rapidly impacts olfactory epithelium and behavior in mice JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep34011 DO - 10.1038/srep34011 ID - Riviere2016 ER - TY - JOUR AU - Roman, F. S. AU - Alescio-Lautier, B. AU - Soumireu-Mourat, B. PY - 1996 DA - 1996// TI - Age-related learning and memory deficits in odor-reward association in rats JO - Neurobiol Aging VL - 17 UR - https://doi.org/10.1016/0197-4580(95)02030-6 DO - 10.1016/0197-4580(95)02030-6 ID - Roman1996 ER - TY - JOUR AU - Rubio, A. AU - Belles, M. AU - Belenguer, G. AU - Vidueira, S. AU - Farinas, I. AU - Nacher, J. PY - 2016 DA - 2016// TI - Characterization and isolation of immature neurons of the adult mouse piriform cortex JO - Dev Neurobiol VL - 76 UR - https://doi.org/10.1002/dneu.22357 DO - 10.1002/dneu.22357 ID - Rubio2016 ER - TY - JOUR AU - Sa-Nguanmoo, P. AU - Tanajak, P. AU - Kerdphoo, S. AU - Jaiwongkam, T. AU - Pratchayasakul, W. AU - Chattipakorn, N. AU - Chattipakorn, S. C. PY - 2017 DA - 2017// TI - SGLT2-inhibitor and DPP-4 inhibitor improve brain function via attenuating mitochondrial dysfunction, insulin resistance, inflammation, and apoptosis in HFD-induced obese rats JO - Toxicol Appl Pharmacol VL - 333 UR - https://doi.org/10.1016/j.taap.2017.08.005 DO - 10.1016/j.taap.2017.08.005 ID - Sa-Nguanmoo2017 ER - TY - JOUR AU - Saiz-Sanchez, D. AU - De la Rosa-Prieto, C. AU - Ubeda-Banon, I. AU - Martinez-Marcos, A. PY - 2015 DA - 2015// TI - Interneurons, tau and amyloid-beta in the piriform cortex in Alzheimer's disease JO - Brain Struct Funct VL - 220 UR - https://doi.org/10.1007/s00429-014-0771-3 DO - 10.1007/s00429-014-0771-3 ID - Saiz-Sanchez2015 ER - TY - JOUR AU - Saiz-Sanchez, D. AU - Flores-Cuadrado, A. AU - Ubeda-Banon, I. AU - de la Rosa-Prieto, C. AU - Martinez-Marcos, A. PY - 2016 DA - 2016// TI - Interneurons in the human olfactory system in Alzheimer's disease JO - Exp Neurol VL - 276 UR - https://doi.org/10.1016/j.expneurol.2015.11.009 DO - 10.1016/j.expneurol.2015.11.009 ID - Saiz-Sanchez2016 ER - TY - JOUR AU - Saiz-Sanchez, D. AU - Ubeda-Banon, I. AU - De la Rosa-Prieto, C. AU - Martinez-Marcos, A. PY - 2012 DA - 2012// TI - Differential expression of interneuron populations and correlation with amyloid-beta deposition in the olfactory cortex of an AbetaPP/PS1 transgenic mouse model of Alzheimer's disease JO - JAD VL - 31 ID - Saiz-Sanchez2012 ER - TY - JOUR AU - Sakamoto, M. AU - Kageyama, R. AU - Imayoshi, I. PY - 2014 DA - 2014// TI - The functional significance of newly born neurons integrated into olfactory bulb circuits JO - Front Neurosci VL - 8 ID - Sakamoto2014 ER - TY - JOUR AU - Sanke, H. AU - Mita, T. AU - Yoshii, H. AU - Yokota, A. AU - Yamashiro, K. AU - Ingaki, N. AU - Onuma, T. AU - Someya, Y. AU - Komiya, K. AU - Tamura, Y. PY - 2014 DA - 2014// TI - Relationship between olfactory dysfunction and cognitive impairment in elderly patients with type 2 diabetes mellitus JO - Diabetes Res Clin Pract VL - 106 UR - https://doi.org/10.1016/j.diabres.2014.09.039 DO - 10.1016/j.diabres.2014.09.039 ID - Sanke2014 ER - TY - JOUR AU - Scheen, A. J. PY - 2015 DA - 2015// TI - A review of gliptins for 2014 JO - Expert Opin Pharmacother VL - 16 UR - https://doi.org/10.1517/14656566.2015.978289 DO - 10.1517/14656566.2015.978289 ID - Scheen2015 ER - TY - JOUR AU - Seki, T. AU - Arai, Y. PY - 1991 DA - 1991// TI - Expression of highly polysialylated NCAM in the neocortex and piriform cortex of the developing and the adult rat JO - Anat Embryol (Berl) VL - 184 UR - https://doi.org/10.1007/BF00957900 DO - 10.1007/BF00957900 ID - Seki1991 ER - TY - JOUR AU - Seubert, J. AU - Laukka, E. J. AU - Rizzuto, D. AU - Hummel, T. AU - Fratiglioni, L. AU - Backman, L. AU - Larsson, M. PY - 2017 DA - 2017// TI - Prevalence and correlates of olfactory dysfunction in old age: a population-based study. The journals of gerontology series a, biological sciences and medical JO - Sciences VL - 72 ID - Seubert2017 ER - TY - JOUR AU - Shapiro, L. A. AU - Ng, K. L. AU - Kinyamu, R. AU - Whitaker-Azmitia, P. AU - Geisert, E. E. AU - Blurton-Jones, M. AU - Zhou, Q. Y. AU - Ribak, C. E. PY - 2007 DA - 2007// TI - Origin, migration and fate of newly generated neurons in the adult rodent piriform cortex JO - Brain Struct Funct VL - 212 UR - https://doi.org/10.1007/s00429-007-0151-3 DO - 10.1007/s00429-007-0151-3 ID - Shapiro2007 ER - TY - JOUR AU - Thiebaud, N. AU - Johnson, M. C. AU - Butler, J. L. AU - Bell, G. A. AU - Ferguson, K. L. AU - Fadool, A. R. AU - Fadool, J. C. AU - Gale, A. M. AU - Gale, D. S. AU - Fadool, D. A. PY - 2014 DA - 2014// TI - Hyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning JO - J Neurosci VL - 34 UR - https://doi.org/10.1523/JNEUROSCI.3366-13.2014 DO - 10.1523/JNEUROSCI.3366-13.2014 ID - Thiebaud2014 ER - TY - STD TI - Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody Iet al (2012) Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell 149: 708–721 Doi https://doi.org/10.1016/j.cell.2012.02.046 ID - ref88 ER - TY - JOUR AU - Wakabayashi, T. AU - Hidaka, R. AU - Fujimaki, S. AU - Asashima, M. AU - Kuwabara, T. PY - 2016 DA - 2016// TI - Diabetes impairs Wnt3 protein-induced neurogenesis in olfactory bulbs via glutamate transporter 1 inhibition JO - J Biol Chem VL - 291 UR - https://doi.org/10.1074/jbc.M115.672857 DO - 10.1074/jbc.M115.672857 ID - Wakabayashi2016 ER - TY - JOUR AU - Xu, W. AU - Caracciolo, B. AU - Wang, H. X. AU - Winblad, B. AU - Backman, L. AU - Qiu, C. AU - Fratiglioni, L. PY - 2010 DA - 2010// TI - Accelerated progression from mild cognitive impairment to dementia in people with diabetes JO - Diabetes VL - 59 UR - https://doi.org/10.2337/db10-0539 DO - 10.2337/db10-0539 ID - Xu2010 ER - TY - STD TI - Xu ZP, Yang SL, Zhao S, Zheng CH, Li HH, Zhang Y, Huang RX, Li MZ, Gao Y, Zhang SJet al (2016) Biomarkers for early diagnostic of mild cognitive impairment in Type-2 diabetes patients: a multicentre, retrospective, nested case-control study. EBioMedicine 5: 105–113 https://doi.org/10.1016/j.ebiom.2016.02.014 ID - ref91 ER - TY - JOUR AU - Young, J. W. AU - Sharkey, J. AU - Finlayson, K. PY - 2009 DA - 2009// TI - Progressive impairment in olfactory working memory in a mouse model of mild cognitive impairment JO - Neurobiol Aging VL - 30 UR - https://doi.org/10.1016/j.neurobiolaging.2007.11.018 DO - 10.1016/j.neurobiolaging.2007.11.018 ID - Young2009 ER - TY - JOUR AU - Zhan, C. AU - Luo, M. PY - 2010 DA - 2010// TI - Diverse patterns of odor representation by neurons in the anterior piriform cortex of awake mice JO - J Neurosci VL - 30 UR - https://doi.org/10.1523/JNEUROSCI.4400-10.2010 DO - 10.1523/JNEUROSCI.4400-10.2010 ID - Zhan2010 ER -