TY - JOUR AU - Al-Mashhadi, S. AU - Simpson, J. E. AU - Heath, P. R. AU - Dickman, M. AU - Forster, G. AU - Matthews, F. E. AU - Brayne, C. AU - Ince, P. G. AU - Wharton, S. B. PY - 2015 DA - 2015// TI - Oxidative glial cell damage associated with white matter lesions in the aging human brain JO - Brain pathology (Zurich, Switzerland) VL - 25 UR - https://doi.org/10.1111/bpa.12216 DO - 10.1111/bpa.12216 ID - Al-Mashhadi2015 ER - TY - JOUR AU - Back, S. A. AU - Gan, X. AU - Li, Y. AU - Rosenberg, P. A. AU - Volpe, J. J. PY - 1998 DA - 1998// TI - Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion JO - J Neurosci VL - 18 ID - Back1998 ER - TY - JOUR AU - Back, S. A. AU - Han, B. H. AU - Luo, N. L. AU - Chricton, C. A. AU - Xanthoudakis, S. AU - Tam, J. AU - Arvin, K. L. AU - Holtzman, D. M. PY - 2002 DA - 2002// TI - Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia JO - J Neurosci VL - 22 ID - Back2002 ER - TY - JOUR AU - Ballatore, C. AU - Lee, V. M. AU - Trojanowski, J. Q. PY - 2007 DA - 2007// TI - Tau-mediated neurodegeneration in Alzheimer's disease and related disorders JO - Nat Rev Neurosci VL - 8 UR - https://doi.org/10.1038/nrn2194 DO - 10.1038/nrn2194 ID - Ballatore2007 ER - TY - STD TI - Bartzokis G (2011) Alzheimer’s disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging 32: 1341-1371 Doi 0.1016/j.Neurobiolaging.2009.08.007 ID - ref5 ER - TY - JOUR AU - Bartzokis, G. AU - Cummings, J. L. AU - Sultzer, D. AU - Henderson, V. W. AU - Nuechterlein, K. H. AU - Mintz, J. PY - 2003 DA - 2003// TI - White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study JO - Arch Neurol VL - 60 UR - https://doi.org/10.1001/archneur.60.3.393 DO - 10.1001/archneur.60.3.393 ID - Bartzokis2003 ER - TY - JOUR AU - Bartzokis, G. AU - Lu, P. H. AU - Mintz, J. PY - 2007 DA - 2007// TI - Human brain myelination and amyloid beta deposition in Alzheimer's disease JO - Alzheimers Dement VL - 3 UR - https://doi.org/10.1016/j.jalz.2007.01.019 DO - 10.1016/j.jalz.2007.01.019 ID - Bartzokis2007 ER - TY - JOUR AU - Bartzokis, G. AU - Sultzer, D. AU - Lu, P. H. AU - Nuechterlein, K. H. AU - Mintz, J. AU - Cummings, J. L. PY - 2004 DA - 2004// TI - Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's disease JO - Neurobiol Aging VL - 25 UR - https://doi.org/10.1016/j.neurobiolaging.2003.09.005 DO - 10.1016/j.neurobiolaging.2003.09.005 ID - Bartzokis2004 ER - TY - STD TI - Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TMet al (2012) Clinical and biomarker changes in dominantly inherited Alzheimer’s disease. N Engl J Med 367: 795–804 Doi https://doi.org/10.1056/NEJMoa1202753 ID - ref9 ER - TY - JOUR AU - Baumann, N. AU - Pham-Dinh, D. PY - 2001 DA - 2001// TI - Biology of oligodendrocyte and myelin in the mammalian central nervous system JO - Physiol Rev VL - 81 UR - https://doi.org/10.1152/physrev.2001.81.2.871 DO - 10.1152/physrev.2001.81.2.871 ID - Baumann2001 ER - TY - JOUR AU - Behrendt, G. AU - Baer, K. AU - Buffo, A. AU - Curtis, M. A. AU - Faull, R. L. AU - Rees, M. I. AU - Gotz, M. AU - Dimou, L. PY - 2013 DA - 2013// TI - Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men JO - Glia VL - 61 UR - https://doi.org/10.1002/glia.22432 DO - 10.1002/glia.22432 ID - Behrendt2013 ER - TY - JOUR AU - Bender, A. R. AU - Volkle, M. C. AU - Raz, N. PY - 2016 DA - 2016// TI - Differential aging of cerebral white matter in middle-aged and older adults: a seven-year follow-up JO - NeuroImage VL - 125 UR - https://doi.org/10.1016/j.neuroimage.2015.10.030 DO - 10.1016/j.neuroimage.2015.10.030 ID - Bender2016 ER - TY - JOUR AU - Benitez, A. AU - Fieremans, E. AU - Jensen, J. H. AU - Falangola, M. F. AU - Tabesh, A. AU - Ferris, S. H. AU - Helpern, J. A. PY - 2014 DA - 2014// TI - White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's disease JO - NeuroImage Clinical VL - 4 UR - https://doi.org/10.1016/j.nicl.2013.11.001 DO - 10.1016/j.nicl.2013.11.001 ID - Benitez2014 ER - TY - JOUR AU - Bennett, D. A. AU - Schneider, J. A. AU - Arvanitakis, Z. AU - Kelly, J. F. AU - Aggarwal, N. T. AU - Shah, R. C. AU - Wilson, R. S. PY - 2006 DA - 2006// TI - Neuropathology of older persons without cognitive impairment from two community-based studies JO - Neurology VL - 66 UR - https://doi.org/10.1212/01.wnl.0000219668.47116.e6 DO - 10.1212/01.wnl.0000219668.47116.e6 ID - Bennett2006 ER - TY - JOUR AU - Bergles, D. E. AU - Roberts, J. D. AU - Somogyi, P. AU - Jahr, C. E. PY - 2000 DA - 2000// TI - Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus JO - Nature VL - 405 UR - https://doi.org/10.1038/35012083 DO - 10.1038/35012083 ID - Bergles2000 ER - TY - JOUR AU - Billings, L. M. AU - Oddo, S. AU - Green, K. N. AU - McGaugh, J. L. AU - LaFerla, F. M. PY - 2005 DA - 2005// TI - Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice JO - Neuron VL - 45 UR - https://doi.org/10.1016/j.neuron.2005.01.040 DO - 10.1016/j.neuron.2005.01.040 ID - Billings2005 ER - TY - JOUR AU - Braak, H. AU - Braak, E. PY - 1996 DA - 1996// TI - Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis JO - Acta Neuropathol VL - 92 UR - https://doi.org/10.1007/s004010050508 DO - 10.1007/s004010050508 ID - Braak1996 ER - TY - JOUR AU - Brickman, A. M. PY - 2013 DA - 2013// TI - Contemplating Alzheimer's disease and the contribution of white matter hyperintensities JO - Curr Neurol Neurosci Rep VL - 13 UR - https://doi.org/10.1007/s11910-013-0415-7 DO - 10.1007/s11910-013-0415-7 ID - Brickman2013 ER - TY - JOUR AU - Brickman, A. M. AU - Provenzano, F. A. AU - Muraskin, J. AU - Manly, J. J. AU - Blum, S. AU - Apa, Z. AU - Stern, Y. AU - Brown, T. R. AU - Luchsinger, J. A. AU - Mayeux, R. PY - 2012 DA - 2012// TI - Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer disease in the community JO - Arch Neurol VL - 69 UR - https://doi.org/10.1001/archneurol.2012.1527 DO - 10.1001/archneurol.2012.1527 ID - Brickman2012 ER - TY - JOUR AU - Brickman, A. M. AU - Schupf, N. AU - Manly, J. J. AU - Stern, Y. AU - Luchsinger, J. A. AU - Provenzano, F. A. AU - Narkhede, A. AU - Razlighi, Q. AU - Collins-Praino, L. AU - Artero, S. PY - 2014 DA - 2014// TI - APOE epsilon4 and risk for Alzheimer's disease: do regionally distributed white matter hyperintensities play a role? JO - Alzheimers Dement VL - 10 UR - https://doi.org/10.1016/j.jalz.2014.07.155 DO - 10.1016/j.jalz.2014.07.155 ID - Brickman2014 ER - TY - JOUR AU - Brickman, A. M. AU - Zahodne, L. B. AU - Guzman, V. A. AU - Narkhede, A. AU - Meier, I. B. AU - Griffith, E. Y. AU - Provenzano, F. A. AU - Schupf, N. AU - Manly, J. J. AU - Stern, Y. PY - 2015 DA - 2015// TI - Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence JO - Neurobiol Aging VL - 36 UR - https://doi.org/10.1016/j.neurobiolaging.2014.07.019 DO - 10.1016/j.neurobiolaging.2014.07.019 ID - Brickman2015 ER - TY - JOUR AU - Brody, B. A. AU - Kinney, H. C. AU - Kloman, A. S. AU - Gilles, F. H. PY - 1987 DA - 1987// TI - Sequence of central nervous system myelination in human infancy. I. An autopsy study of myelination JO - J Neuropathol Exp Neurol VL - 46 UR - https://doi.org/10.1097/00005072-198705000-00005 DO - 10.1097/00005072-198705000-00005 ID - Brody1987 ER - TY - JOUR AU - Brown, W. R. AU - Thore, C. R. PY - 2011 DA - 2011// TI - Review: cerebral microvascular pathology in ageing and neurodegeneration JO - Neuropathol Appl Neurobiol VL - 37 UR - https://doi.org/10.1111/j.1365-2990.2010.01139.x DO - 10.1111/j.1365-2990.2010.01139.x ID - Brown2011 ER - TY - JOUR AU - Chittajallu, R. AU - Aguirre, A. AU - Gallo, V. PY - 2004 DA - 2004// TI - NG2-positive cells in the mouse white and grey matter display distinct physiological properties JO - J Physiol VL - 561 UR - https://doi.org/10.1113/jphysiol.2004.074252 DO - 10.1113/jphysiol.2004.074252 ID - Chittajallu2004 ER - TY - JOUR AU - Collins-Praino, L. E. AU - Francis, Y. I. AU - Griffith, E. Y. AU - Wiegman, A. F. AU - Urbach, J. AU - Lawton, A. AU - Honig, L. S. AU - Cortes, E. AU - Vonsattel, J. P. AU - Canoll, P. D. PY - 2014 DA - 2014// TI - Soluble amyloid beta levels are elevated in the white matter of Alzheimer’s patients, independent of cortical plaque severity JO - Acta Neuropathol Commun VL - 2 ID - Collins-Praino2014 ER - TY - JOUR AU - De Leeuw, F. E. AU - Barkhof, F. AU - Scheltens, P. PY - 2004 DA - 2004// TI - Alzheimer’s disease--one clinical syndrome, two radiological expressions: a study on blood pressure JO - J Neurol Neurosurg Psychiatry VL - 75 UR - https://doi.org/10.1136/jnnp.2003.030189 DO - 10.1136/jnnp.2003.030189 ID - De Leeuw2004 ER - TY - JOUR AU - Deng, W. AU - Wang, H. AU - Rosenberg, P. A. AU - Volpe, J. J. AU - Jensen, F. E. PY - 2004 DA - 2004// TI - Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress JO - Proc Natl Acad Sci U S A VL - 101 UR - https://doi.org/10.1073/pnas.0307850101 DO - 10.1073/pnas.0307850101 ID - Deng2004 ER - TY - JOUR AU - Desai, M. K. AU - Guercio, B. J. AU - Narrow, W. C. AU - Bowers, W. J. PY - 2011 DA - 2011// TI - An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction JO - Glia VL - 59 UR - https://doi.org/10.1002/glia.21131 DO - 10.1002/glia.21131 ID - Desai2011 ER - TY - JOUR AU - Desai, M. K. AU - Mastrangelo, M. A. AU - Ryan, D. A. AU - Sudol, K. L. AU - Narrow, W. C. AU - Bowers, W. J. PY - 2010 DA - 2010// TI - Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target JO - Am J Pathol VL - 177 UR - https://doi.org/10.2353/ajpath.2010.100087 DO - 10.2353/ajpath.2010.100087 ID - Desai2010 ER - TY - JOUR AU - Desai, M. K. AU - Sudol, K. L. AU - Janelsins, M. C. AU - Mastrangelo, M. A. AU - Frazer, M. E. AU - Bowers, W. J. PY - 2009 DA - 2009// TI - Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology JO - Glia VL - 57 UR - https://doi.org/10.1002/glia.20734 DO - 10.1002/glia.20734 ID - Desai2009 ER - TY - JOUR AU - Erten-Lyons, D. AU - Woltjer, R. AU - Kaye, J. AU - Mattek, N. AU - Dodge, H. H. AU - Green, S. AU - Tran, H. AU - Howieson, D. B. AU - Wild, K. AU - Silbert, L. C. PY - 2013 DA - 2013// TI - Neuropathologic basis of white matter hyperintensity accumulation with advanced age JO - Neurology VL - 81 UR - https://doi.org/10.1212/WNL.0b013e3182a43e45 DO - 10.1212/WNL.0b013e3182a43e45 ID - Erten-Lyons2013 ER - TY - JOUR AU - Fields, R. D. PY - 2015 DA - 2015// TI - A new mechanism of nervous system plasticity: activity-dependent myelination JO - Nat Rev Neurosci VL - 16 UR - https://doi.org/10.1038/nrn4023 DO - 10.1038/nrn4023 ID - Fields2015 ER - TY - JOUR AU - Fischer, F. U. AU - Wolf, D. AU - Scheurich, A. AU - Fellgiebel, A. PY - 2015 DA - 2015// TI - Altered whole-brain white matter networks in preclinical Alzheimer's disease JO - NeuroImage Clinical VL - 8 UR - https://doi.org/10.1016/j.nicl.2015.06.007 DO - 10.1016/j.nicl.2015.06.007 ID - Fischer2015 ER - TY - JOUR AU - French, H. M. AU - Reid, M. AU - Mamontov, P. AU - Simmons, R. A. AU - Grinspan, J. B. PY - 2009 DA - 2009// TI - Oxidative stress disrupts oligodendrocyte maturation JO - J Neurosci Res VL - 87 UR - https://doi.org/10.1002/jnr.22139 DO - 10.1002/jnr.22139 ID - French2009 ER - TY - JOUR AU - Gagyi, E. AU - Kormos, B. AU - Castellanos, K. J. AU - Valyi-Nagy, K. AU - Korneff, D. AU - LoPresti, P. AU - Woltjer, R. AU - Valyi-Nagy, T. PY - 2012 DA - 2012// TI - Decreased oligodendrocyte nuclear diameter in Alzheimer's disease and Lewy body dementia JO - Brain pathology (Zurich, Switzerland) VL - 22 UR - https://doi.org/10.1111/j.1750-3639.2012.00595.x DO - 10.1111/j.1750-3639.2012.00595.x ID - Gagyi2012 ER - TY - JOUR AU - Gao, J. AU - Cheung, R. T. AU - Lee, T. M. AU - Chu, L. W. AU - Chan, Y. S. AU - Mak, H. K. AU - Zhang, J. X. AU - Qiu, D. AU - Fung, G. AU - Cheung, C. PY - 2011 DA - 2011// TI - Possible retrogenesis observed with fiber tracking: an anteroposterior pattern of white matter disintegrity in normal aging and Alzheimer’s disease JO - Journal of Alzheimer’s disease : JAD VL - 26 ID - Gao2011 ER - TY - JOUR AU - Gogate, N. AU - Verma, L. AU - Zhou, J. M. AU - Milward, E. AU - Rusten, R. AU - O'Connor, M. AU - Kufta, C. AU - Kim, J. AU - Hudson, L. AU - Dubois-Dalcq, M. PY - 1994 DA - 1994// TI - Plasticity in the adult human oligodendrocyte lineage JO - The Journal of neuroscience : the official journal of the Society for Neuroscience VL - 14 ID - Gogate1994 ER - TY - JOUR AU - Gouw, A. A. AU - Seewann, A. AU - Vrenken, H. AU - van der Flier, W. M. AU - Rozemuller, J. M. AU - Barkhof, F. AU - Scheltens, P. AU - Geurts, J. J. PY - 2008 DA - 2008// TI - Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology JO - Brain : a journal of neurology VL - 131 UR - https://doi.org/10.1093/brain/awn265 DO - 10.1093/brain/awn265 ID - Gouw2008 ER - TY - STD TI - Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JWet al (2008) Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet (London, England) 372: 216-223 Doi https://doi.org/10.1016/s0140-6736(08)61075-2 ID - ref39 ER - TY - JOUR AU - Horiuchi, M. AU - Maezawa, I. AU - Itoh, A. AU - Wakayama, K. AU - Jin, L. W. AU - Itoh, T. AU - Decarli, C. PY - 2012 DA - 2012// TI - Amyloid beta1-42 oligomer inhibits myelin sheet formation in vitro JO - Neurobiol Aging VL - 33 UR - https://doi.org/10.1016/j.neurobiolaging.2010.05.007 DO - 10.1016/j.neurobiolaging.2010.05.007 ID - Horiuchi2012 ER - TY - JOUR AU - Jantaratnotai, N. AU - Ryu, J. K. AU - Kim, S. U. AU - McLarnon, J. G. PY - 2003 DA - 2003// TI - Amyloid beta peptide-induced corpus callosum damage and glial activation in vivo JO - Neuroreport VL - 14 UR - https://doi.org/10.1097/00001756-200308060-00005 DO - 10.1097/00001756-200308060-00005 ID - Jantaratnotai2003 ER - TY - JOUR AU - Jorgensen, A. M. AU - Marner, L. AU - Pakkenberg, B. PY - 2008 DA - 2008// TI - No change in total length of white matter fibers in Alzheimer's disease JO - Neuroscience VL - 157 UR - https://doi.org/10.1016/j.neuroscience.2008.06.075 DO - 10.1016/j.neuroscience.2008.06.075 ID - Jorgensen2008 ER - TY - JOUR AU - Juurlink, B. H. AU - Thorburne, S. K. AU - Hertz, L. PY - 1998 DA - 1998// TI - Peroxide-scavenging deficit underlies oligodendrocyte susceptibility to oxidative stress JO - Glia VL - 22 UR - https://doi.org/3.0.CO;2-6 DO - 3.0.CO;2-6 ID - Juurlink1998 ER - TY - JOUR AU - Kapfhammer, J. P. AU - Schwab, M. E. PY - 1994 DA - 1994// TI - Inverse patterns of myelination and GAP-43 expression in the adult CNS: neurite growth inhibitors as regulators of neuronal plasticity? JO - J Comp Neurol VL - 340 UR - https://doi.org/10.1002/cne.903400206 DO - 10.1002/cne.903400206 ID - Kapfhammer1994 ER - TY - JOUR AU - Kelleher, R. J. AU - Shen, J. PY - 2017 DA - 2017// TI - Presenilin-1 mutations and Alzheimer's disease JO - Proc Natl Acad Sci U S A VL - 114 UR - https://doi.org/10.1073/pnas.1619574114 DO - 10.1073/pnas.1619574114 ID - Kelleher2017 ER - TY - JOUR AU - Kukley, M. AU - Capetillo-Zarate, E. AU - Dietrich, D. PY - 2007 DA - 2007// TI - Vesicular glutamate release from axons in white matter JO - Nat Neurosci VL - 10 UR - https://doi.org/10.1038/nn1850 DO - 10.1038/nn1850 ID - Kukley2007 ER - TY - JOUR AU - Lebel, C. AU - Beaulieu, C. PY - 2011 DA - 2011// TI - Longitudinal development of human brain wiring continues from childhood into adulthood JO - J Neurosci VL - 31 UR - https://doi.org/10.1523/JNEUROSCI.5302-10.2011 DO - 10.1523/JNEUROSCI.5302-10.2011 ID - Lebel2011 ER - TY - JOUR AU - Lee, J. T. AU - Xu, J. AU - Lee, J. M. AU - Ku, G. AU - Han, X. AU - Yang, D. I. AU - Chen, S. AU - Hsu, C. Y. PY - 2004 DA - 2004// TI - Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway JO - J Cell Biol VL - 164 UR - https://doi.org/10.1083/jcb.200307017 DO - 10.1083/jcb.200307017 ID - Lee2004 ER - TY - JOUR AU - Lee, S. AU - Viqar, F. AU - Zimmerman, M. E. AU - Narkhede, A. AU - Tosto, G. AU - Benzinger, T. L. AU - Marcus, D. S. AU - Fagan, A. M. AU - Goate, A. AU - Fox, N. C. PY - 2016 DA - 2016// TI - White matter hyperintensities are a core feature of Alzheimer's disease: evidence from the dominantly inherited Alzheimer network JO - Ann Neurol VL - 79 UR - https://doi.org/10.1002/ana.24647 DO - 10.1002/ana.24647 ID - Lee2016 ER - TY - JOUR AU - Marner, L. AU - Nyengaard, J. R. AU - Tang, Y. AU - Pakkenberg, B. PY - 2003 DA - 2003// TI - Marked loss of myelinated nerve fibers in the human brain with age JO - J Comp Neurol VL - 462 UR - https://doi.org/10.1002/cne.10714 DO - 10.1002/cne.10714 ID - Marner2003 ER - TY - STD TI - Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcao A, Xiao L, Li H, Haring M, Hochgerner H, Romanov RAet al (2016) Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system. Science (New York, NY) 352: 1326-1329 Doi https://doi.org/10.1126/science.aaf6463 ID - ref51 ER - TY - JOUR AU - Mason, J. L. AU - Langaman, C. AU - Morell, P. AU - Suzuki, K. AU - Matsushima, G. K. PY - 2001 DA - 2001// TI - Episodic demyelination and subsequent remyelination within the murine central nervous system: changes in axonal calibre JO - Neuropathol Appl Neurobiol VL - 27 UR - https://doi.org/10.1046/j.0305-1846.2001.00301.x DO - 10.1046/j.0305-1846.2001.00301.x ID - Mason2001 ER - TY - JOUR AU - Matute, C. PY - 2010 DA - 2010// TI - Calcium dyshomeostasis in white matter pathology JO - Cell Calcium VL - 47 UR - https://doi.org/10.1016/j.ceca.2009.12.004 DO - 10.1016/j.ceca.2009.12.004 ID - Matute2010 ER - TY - JOUR AU - Matute, C. PY - 2006 DA - 2006// TI - Oligodendrocyte NMDA receptors: a novel therapeutic target JO - Trends Mol Med VL - 12 UR - https://doi.org/10.1016/j.molmed.2006.05.004 DO - 10.1016/j.molmed.2006.05.004 ID - Matute2006 ER - TY - JOUR AU - Matute, C. AU - Alberdi, E. AU - Domercq, M. AU - Sanchez-Gomez, M. V. AU - Perez-Samartin, A. AU - Rodriguez-Antiguedad, A. AU - Perez-Cerda, F. PY - 2007 DA - 2007// TI - Excitotoxic damage to white matter JO - J Anat VL - 210 UR - https://doi.org/10.1111/j.1469-7580.2007.00733.x DO - 10.1111/j.1469-7580.2007.00733.x ID - Matute2007 ER - TY - JOUR AU - McAleese, K. E. AU - Firbank, M. AU - Dey, M. AU - Colloby, S. J. AU - Walker, L. AU - Johnson, M. AU - Beverley, J. R. AU - Taylor, J. P. AU - Thomas, A. J. AU - O’Brien, J. T. PY - 2015 DA - 2015// TI - Cortical tau load is associated with white matter hyperintensities JO - Acta neuropathologica communications VL - 3 UR - https://doi.org/10.1186/s40478-015-0240-0 DO - 10.1186/s40478-015-0240-0 ID - McAleese2015 ER - TY - STD TI - McAleese KE, Walker L, Graham S, Moya ELJ, Johnson M, Erskine D, Colloby SJ, Dey M, Martin-Ruiz C, Taylor JP et al (2017) Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease. Acta neuropathologica. https://doi.org/10.1007/s00401-017-1738-2 ID - ref57 ER - TY - JOUR AU - McKenzie, I. A. AU - Ohayon, D. AU - Li, H. AU - de Faria, J. P. AU - Emery, B. AU - Tohyama, K. AU - Richardson, W. D. PY - 2014 DA - 2014// TI - Motor skill learning requires active central myelination JO - Science (New York, NY) VL - 346 UR - https://doi.org/10.1126/science.1254960 DO - 10.1126/science.1254960 ID - McKenzie2014 ER - TY - JOUR AU - Menn, B. AU - Garcia-Verdugo, J. M. AU - Yaschine, C. AU - Gonzalez-Perez, O. AU - Rowitch, D. AU - Alvarez-Buylla, A. PY - 2006 DA - 2006// TI - Origin of oligodendrocytes in the subventricular zone of the adult brain JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.1299-06.2006 DO - 10.1523/JNEUROSCI.1299-06.2006 ID - Menn2006 ER - TY - JOUR AU - Pak, K. AU - Chan, S. L. AU - Mattson, M. P. PY - 2003 DA - 2003// TI - Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice JO - NeuroMolecular Med VL - 3 UR - https://doi.org/10.1385/NMM:3:1:53 DO - 10.1385/NMM:3:1:53 ID - Pak2003 ER - TY - JOUR AU - Pantoni, L. AU - Garcia, J. H. PY - 1997 DA - 1997// TI - Cognitive impairment and cellular/vascular changes in the cerebral white matter JO - Ann N Y Acad Sci VL - 826 UR - https://doi.org/10.1111/j.1749-6632.1997.tb48463.x DO - 10.1111/j.1749-6632.1997.tb48463.x ID - Pantoni1997 ER - TY - JOUR AU - Price, J. L. AU - McKeel, D. W. AU - Buckles, V. D. AU - Roe, C. M. AU - Xiong, C. AU - Grundman, M. AU - Hansen, L. A. AU - Petersen, R. C. AU - Parisi, J. E. AU - Dickson, D. W. PY - 2009 DA - 2009// TI - Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease JO - Neurobiol Aging VL - 30 UR - https://doi.org/10.1016/j.neurobiolaging.2009.04.002 DO - 10.1016/j.neurobiolaging.2009.04.002 ID - Price2009 ER - TY - JOUR AU - Prins, N. D. AU - Scheltens, P. PY - 2015 DA - 2015// TI - White matter hyperintensities, cognitive impairment and dementia: an update JO - Nat Rev Neurol VL - 11 UR - https://doi.org/10.1038/nrneurol.2015.10 DO - 10.1038/nrneurol.2015.10 ID - Prins2015 ER - TY - JOUR AU - Raz, N. AU - Yang, Y. AU - Dahle, C. L. AU - Land, S. PY - 2012 DA - 2012// TI - Volume of white matter hyperintensities in healthy adults: contribution of age, vascular risk factors, and inflammation-related genetic variants JO - Biochim Biophys Acta VL - 1822 UR - https://doi.org/10.1016/j.bbadis.2011.08.007 DO - 10.1016/j.bbadis.2011.08.007 ID - Raz2012 ER - TY - JOUR AU - Reisberg, B. AU - Franssen, E. H. AU - Hasan, S. M. AU - Monteiro, I. AU - Boksay, I. AU - Souren, L. E. AU - Kenowsky, S. AU - Auer, S. R. AU - Elahi, S. AU - Kluger, A. PY - 1999 DA - 1999// TI - Retrogenesis: clinical, physiologic, and pathologic mechanisms in brain aging, Alzheimer's and other dementing processes JO - Eur Arch Psychiatry Clin Neurosci VL - 249 UR - https://doi.org/10.1007/PL00014170 DO - 10.1007/PL00014170 ID - Reisberg1999 ER - TY - JOUR AU - Reisberg, B. AU - Franssen, E. H. AU - Souren, L. E. AU - Auer, S. R. AU - Akram, I. AU - Kenowsky, S. PY - 2002 DA - 2002// TI - Evidence and mechanisms of retrogenesis in Alzheimer's and other dementias: management and treatment import JO - Am J Alzheimers Dis Other Demen VL - 17 UR - https://doi.org/10.1177/153331750201700411 DO - 10.1177/153331750201700411 ID - Reisberg2002 ER - TY - JOUR AU - Roher, A. E. AU - Weiss, N. AU - Kokjohn, T. A. AU - Kuo, Y. M. AU - Kalback, W. AU - Anthony, J. AU - Watson, D. AU - Luehrs, D. C. AU - Sue, L. AU - al, W. D. PY - 2002 DA - 2002// TI - Increased a beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease JO - Biochemistry VL - 41 UR - https://doi.org/10.1021/bi026173d DO - 10.1021/bi026173d ID - Roher2002 ER - TY - JOUR AU - Scheltens, P. AU - Barkhof, F. AU - Leys, D. AU - Wolters, E. C. AU - Ravid, R. AU - Kamphorst, W. PY - 1995 DA - 1995// TI - Histopathologic correlates of white matter changes on MRI in Alzheimer's disease and normal aging JO - Neurology VL - 45 UR - https://doi.org/10.1212/WNL.45.5.883 DO - 10.1212/WNL.45.5.883 ID - Scheltens1995 ER - TY - JOUR AU - Schuff, N. AU - Matsumoto, S. AU - Kmiecik, J. AU - Studholme, C. AU - Du, A. AU - Ezekiel, F. AU - Miller, B. L. AU - Kramer, J. H. AU - Jagust, W. J. AU - Chui, H. C. PY - 2009 DA - 2009// TI - Cerebral blood flow in ischemic vascular dementia and Alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging JO - Alzheimers Dement VL - 5 UR - https://doi.org/10.1016/j.jalz.2009.04.1233 DO - 10.1016/j.jalz.2009.04.1233 ID - Schuff2009 ER - TY - JOUR AU - Schwab, M. E. PY - 1990 DA - 1990// TI - Myelin-associated inhibitors of neurite growth and regeneration in the CNS JO - Trends Neurosci VL - 13 UR - https://doi.org/10.1016/0166-2236(90)90098-U DO - 10.1016/0166-2236(90)90098-U ID - Schwab1990 ER - TY - JOUR AU - Scott, J. A. AU - Braskie, M. N. AU - Tosun, D. AU - Thompson, P. M. AU - Weiner, M. AU - DeCarli, C. AU - Carmichael, O. T. PY - 2015 DA - 2015// TI - Cerebral amyloid and hypertension are independently associated with white matter lesions in elderly JO - Front Aging Neurosci VL - 7 UR - https://doi.org/10.3389/fnagi.2015.00221 DO - 10.3389/fnagi.2015.00221 ID - Scott2015 ER - TY - JOUR AU - Selkoe, D. J. PY - 2011 DA - 2011// TI - Resolving controversies on the path to Alzheimer's therapeutics JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2460 DO - 10.1038/nm.2460 ID - Selkoe2011 ER - TY - JOUR AU - Selkoe, D. J. AU - Hardy, J. PY - 2016 DA - 2016// TI - The amyloid hypothesis of Alzheimer's disease at 25 years JO - EMBO Mol Med VL - 8 UR - https://doi.org/10.15252/emmm.201606210 DO - 10.15252/emmm.201606210 ID - Selkoe2016 ER - TY - JOUR AU - Simpson, J. E. AU - Fernando, M. S. AU - Clark, L. AU - Ince, P. G. AU - Matthews, F. AU - Forster, G. AU - O'Brien, J. T. AU - Barber, R. AU - Kalaria, R. N. AU - Brayne, C. PY - 2007 DA - 2007// TI - White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses JO - Neuropathol Appl Neurobiol VL - 33 UR - https://doi.org/10.1111/j.1365-2990.2007.00828.x DO - 10.1111/j.1365-2990.2007.00828.x ID - Simpson2007 ER - TY - JOUR AU - Sims, R. AU - Hollingworth, P. AU - Moskvina, V. AU - Dowzell, K. AU - O'Donovan, M. C. AU - Powell, J. AU - Lovestone, S. AU - Brayne, C. AU - Rubinsztein, D. AU - Owen, M. J. PY - 2009 DA - 2009// TI - Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease JO - Neurosci Lett VL - 461 UR - https://doi.org/10.1016/j.neulet.2009.05.051 DO - 10.1016/j.neulet.2009.05.051 ID - Sims2009 ER - TY - JOUR AU - Stricker, N. H. AU - Schweinsburg, B. C. AU - Delano-Wood, L. AU - Wierenga, C. E. AU - Bangen, K. J. AU - Haaland, K. Y. AU - Frank, L. R. AU - Salmon, D. P. AU - Bondi, M. W. PY - 2009 DA - 2009// TI - Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis JO - NeuroImage VL - 45 UR - https://doi.org/10.1016/j.neuroimage.2008.11.027 DO - 10.1016/j.neuroimage.2008.11.027 ID - Stricker2009 ER - TY - JOUR AU - Thorburne, S. K. AU - Juurlink, B. H. PY - 1996 DA - 1996// TI - Low glutathione and high iron govern the susceptibility of oligodendroglial precursors to oxidative stress JO - J Neurochem VL - 67 UR - https://doi.org/10.1046/j.1471-4159.1996.67031014.x DO - 10.1046/j.1471-4159.1996.67031014.x ID - Thorburne1996 ER - TY - JOUR AU - Tosto, G. AU - Zimmerman, M. E. AU - Carmichael, O. T. AU - Brickman, A. M. PY - 2014 DA - 2014// TI - Predicting aggressive decline in mild cognitive impairment: the importance of white matter hyperintensities JO - JAMA neurology VL - 71 UR - https://doi.org/10.1001/jamaneurol.2014.667 DO - 10.1001/jamaneurol.2014.667 ID - Tosto2014 ER - TY - JOUR AU - Tosto, G. AU - Zimmerman, M. E. AU - Hamilton, J. L. AU - Carmichael, O. T. AU - Brickman, A. M. PY - 2015 DA - 2015// TI - The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment JO - Alzheimers Dement VL - 11 UR - https://doi.org/10.1016/j.jalz.2015.05.014 DO - 10.1016/j.jalz.2015.05.014 ID - Tosto2015 ER - TY - JOUR AU - Tsai, H. H. AU - Niu, J. AU - Munji, R. AU - Davalos, D. AU - Chang, J. AU - Zhang, H. AU - Tien, A. C. AU - Kuo, C. J. AU - Chan, J. R. AU - Daneman, R. PY - 2016 DA - 2016// TI - Oligodendrocyte precursors migrate along vasculature in the developing nervous system JO - Science (New York, NY) VL - 351 UR - https://doi.org/10.1126/science.aad3839 DO - 10.1126/science.aad3839 ID - Tsai2016 ER - TY - JOUR AU - Tse, K. H. AU - Herrup, K. PY - 2017 DA - 2017// TI - DNA damage in the oligodendrocyte lineage and its role in brain aging JO - Mech Ageing Dev VL - 161 UR - https://doi.org/10.1016/j.mad.2016.05.006 DO - 10.1016/j.mad.2016.05.006 ID - Tse2017 ER - TY - STD TI - Tse KH, Herrup K (2017) Re-imagining Alzheimer’s disease - the diminishing importance of amyloid and a glimpse of what lies ahead. J neurochemistry. https://doi.org/10.1111/jnc.14079 ID - ref82 ER - TY - JOUR AU - Vlkolinsky, R. AU - Cairns, N. AU - Fountoulakis, M. AU - Lubec, G. PY - 2001 DA - 2001// TI - Decreased brain levels of 2’,3’-cyclic nucleotide-3’-phosphodiesterase in down syndrome and Alzheimer’s disease JO - Neurobiol Aging VL - 22 UR - https://doi.org/10.1016/S0197-4580(01)00218-4 DO - 10.1016/S0197-4580(01)00218-4 ID - Vlkolinsky2001 ER - TY - STD TI - Xu J, Chen S, Ahmed SH, Chen H, Ku G, Goldberg MP, Hsu CY (2001) Amyloid-beta peptides are cytotoxic to oligodendrocytes. The journal of neuroscience : the official journal of the Society for Neuroscience 21: Rc118 ID - ref84 ER - TY - JOUR AU - Yuen, T. J. AU - Silbereis, J. C. AU - Griveau, A. AU - Chang, S. M. AU - Daneman, R. AU - Fancy, S. P. AU - Zahed, H. AU - Maltepe, E. AU - Rowitch, D. H. PY - 2014 DA - 2014// TI - Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis JO - Cell VL - 158 UR - https://doi.org/10.1016/j.cell.2014.04.052 DO - 10.1016/j.cell.2014.04.052 ID - Yuen2014 ER - TY - JOUR AU - Zhao, Z. AU - Nelson, A. R. AU - Betsholtz, C. AU - Zlokovic, B. V. PY - 2015 DA - 2015// TI - Establishment and dysfunction of the blood-brain barrier JO - Cell VL - 163 UR - https://doi.org/10.1016/j.cell.2015.10.067 DO - 10.1016/j.cell.2015.10.067 ID - Zhao2015 ER -