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Table 1 Summary of Peripheral Nerve Stain with C5b-9

From: Diffuse microvascular C5b-9 deposition is a common feature in muscle and nerve biopsies from diabetic patients

Disease Total (n) 0 1+ 2+ 1+ or 2+
Diabetic (Total) 63 7 28 28 /44.4% 56 /88.9%
 Amyotrophy 10 0 1 9 10/100%
 Autoimmunea 9 3 5 1 4/66.7%
 CIDP 4 1 0 3 3/75%
 SMPN 37 3 19 15 34/91.9%
 Otherb 3 0 3 0 3/100%
Non-Diabetic (Total) 29 22 5 2/6.9% 7/24.1%
 CIDP 11 9 2 0 2/18.1%
 GBS 2 1 0 1 1/50%
 Hereditary 8 6 1 1 2/25%
 Idiopathic PN 4 4 0 0 0/0%
 Mononeuropathy multiplex 3 2 1 0 1/33.3%
 Amyloidosis 1 0 1 0 1/100%
Unknown Diabetic Status (Total) 25 12 11 2/8.0% 13/52.0%
 Amyloid neuropathy 6 5 1 0 1/16.7%
 CIDP 6 3 3 0 3/50%
 Hereditary 1 1 0 0 0/0
 Mononeuropathy multiplex 4 0 3 1 4/100%
 Idiopathic PN 3 2 0 1 1/33%
 Microvascular sclerosis 5 1 4 0 4/80%
  1. a: The “autoimmune” category under diabetic group includes: lupus, rheumatoid arthritis, Sjogren’s, polyarteritis nodosum, Crohn’s disease, sarcoidosis, paraneoplastic
  2. b: The “other” category under diabetic group includes one case each of: lymphoma plexopathy, post-surgical neuropathy, and anti-GM1 motor neuropathy
  3. Abbreviations: CIDP chronic inflammatory demyelinating polyneuropathy, SMPN sensory motor polyneuropathy, GBS Gillian Barré Syndrome, PN polyneuropathy