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Table 1 Summary of Peripheral Nerve Stain with C5b-9

From: Diffuse microvascular C5b-9 deposition is a common feature in muscle and nerve biopsies from diabetic patients

Disease

Total (n)

0

1+

2+

1+ or 2+

Diabetic (Total)

63

7

28

28 /44.4%

56 /88.9%

 Amyotrophy

10

0

1

9

10/100%

 Autoimmunea

9

3

5

1

4/66.7%

 CIDP

4

1

0

3

3/75%

 SMPN

37

3

19

15

34/91.9%

 Otherb

3

0

3

0

3/100%

Non-Diabetic (Total)

29

22

5

2/6.9%

7/24.1%

 CIDP

11

9

2

0

2/18.1%

 GBS

2

1

0

1

1/50%

 Hereditary

8

6

1

1

2/25%

 Idiopathic PN

4

4

0

0

0/0%

 Mononeuropathy multiplex

3

2

1

0

1/33.3%

 Amyloidosis

1

0

1

0

1/100%

Unknown Diabetic Status (Total)

25

12

11

2/8.0%

13/52.0%

 Amyloid neuropathy

6

5

1

0

1/16.7%

 CIDP

6

3

3

0

3/50%

 Hereditary

1

1

0

0

0/0

 Mononeuropathy multiplex

4

0

3

1

4/100%

 Idiopathic PN

3

2

0

1

1/33%

 Microvascular sclerosis

5

1

4

0

4/80%

  1. a: The “autoimmune” category under diabetic group includes: lupus, rheumatoid arthritis, Sjogren’s, polyarteritis nodosum, Crohn’s disease, sarcoidosis, paraneoplastic
  2. b: The “other” category under diabetic group includes one case each of: lymphoma plexopathy, post-surgical neuropathy, and anti-GM1 motor neuropathy
  3. Abbreviations: CIDP chronic inflammatory demyelinating polyneuropathy, SMPN sensory motor polyneuropathy, GBS Gillian Barré Syndrome, PN polyneuropathy