Fig. 1

C5b-9 Grading Scheme in Muscle and Nerve. All muscle and nerve cases are scored 0, 1+ or 2+ based on endomysial (muscle) and/or endoneurial vessel (nerve) stains. a Muscle: 0: no capillary stain. Isolated weak granular stain allowed. Perimysial artery stain (arrow) was not considered pathological and served as internal control. b Nerve: 0: no endoneurial staining. Rare subperineurial or septal vessel stain or very weak granular vessel stain were still considered negative stain. Perineurium stain (arrow) was not considered pathological and served as internal control. c Muscle: 1+: Unequivocal circumferential capillary stain but focal or weak. d Nerve: 1+: Variable endoneurial vessel stain, majority weaker than perineurium. e Muscle: 2+: patchy or diffuse strong circumferential capillary stain. f Nerve: 3+: Circumferential stain in multiple vessels per fascicle, most equal to or stronger than perineurium