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Fig. 11 | Acta Neuropathologica Communications

Fig. 11

From: Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis

Fig. 11

Surfen injected 2 days after LPC increases local expression of CSPG and Iba-1 with increased cell counts at day 7. a Left sided linear graphic shows treatment schedule. Representative immunofluorescence images are shown for Iba-1,CSPGexpression in groups indicated. Merge image (×100 magnification)shows no overlap for Iba-1 and CSPG. Higher magnification merge image (×250) was used to visualize DAPI nuclear staining for cell counts. b Summary data for Iba-1 and CSPG expression. c. Summary data for cell counts. N = 3 mice per group significance compares surfen with vehicle (* = P < 0.05); Scale bars = 100 μm

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