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Fig. 10 | Acta Neuropathologica Communications

Fig. 10

From: Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis

Fig. 10

Surfen injected 2 days after LPC prevents remyelination at day 7. a Representative electron micrographs for the normal corpus callosum and day 7 lesions in mice injected with vehicle or surfen 2 days after LPC. Scale bars = 50 μm. Higher magnification insets are also included with each micrograph. b Summary data for G-ratios. Left panel shows individual G ratios for axons in each group, with superimposed mean ± SEM. Significant differences between groups are indicated above linking cross bars (* = P < 0.05). c Frequency distribution plot using pseudocolor for each group. N indicates number of mice used to obtain the data

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Acta Neuropathologica Communications

ISSN: 2051-5960

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