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Table 1 Summary of the AD, old and young cohorts

From: Pyroglutamate and Isoaspartate modified Amyloid-Beta in ageing and Alzheimer’s disease

Case

Gender

Age at death

APOE status

Braak stage

Dementia duration (years)

AD

15F:12M

63–88

20ε4+: 5ε4_

IV-VI

3–17

OC (n = 32)

16F:16M

64–97

5ε4+: 27ε4_

0-III

n/a

YC (n = 11)

6F:5M

26–62

n/d

n/d

n/a

  1. n/a non-applicable
  2. n/d non-determined