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Table 1 Patient information

From: Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease

 

RRMS

AQP4-Ab NMOSD

MOG-Ab

Number of patients

34

54

20

Age, mean (range), y

41 (18–60)

53 (22–83)*†

39 (16–70)

Gender, No. female (% female)

25 (74)

46 (85)

9 (45)

EDSS, median (range)

4 (0–7)

3 (0–8)

2 (0–8)

Disease duration, median (range), months

89 (1–301)

70 (3–270)

16 (1–420)*~

Time since relapse, median (range), months

23 (0–133)

22 (0–108)

8 (1–39)*~

On oral prednisolone, %

0%

85%

35%

On prednisolone, mean dose mg

0

12

14

On azathioprine, %

0

49

5

On methotrexate, %

0

11

5

On mycophenolate, %

0

19

5

On interferon β, %

15

0

5

On glatiramer, %

12

0

0

On fingolimod, %

12

0

0

On dimethyl fumarate, %

12

3

0

On natalizumab, %

15

0

0

  1. The Kolmogorov-Smirnov test was used to identify significant differences of each class compared to RRMS (*), AQP4-Ab NMOSD (~), or MOG-Ab disease (†)