Fig. 1
From: Clinical and neuropathological features of ALS/FTD with TIA1 mutations
Pedigree of family UBCU2. Family of European ancestry showing an autosomal dominant pattern of inheritance of ALS ± dementia. Black symbols represent clinically affected individuals and diagonal lines indicate those who are deceased. Genetic analysis was performed on the proband (1), her affected niece (14) and her early affected sister (2); all of whom carried the P362L mutation in TIA1