The chronically inflamed central nervous system provides niches for long-lived plasma cells

Table 3 Features of EAE development after disease induction and additional boost

	Incidence	Day of onset	Maximum score	Number of animals without relapse after boost	Number of animals with signs occuring after boost only
EAE induction	69/88 (78,4%)	12,3 ± 1,8	2,1 ± 1,2	–	–
Boost	59/88 (67,1%)^a	36,1 ± 1,6^b	2,1 ± 1,0^c	15/88 (17,1%)^d	9/88 (10,2%)

^aIncrease of scores of ≥0,5
^bAt day 28 boost was performed
^cIncludes clinical scores from animals with constant scores after boost
^dAnimals developed peak after EAE induction, but scores remained stable after boost

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