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Table 1 Characteristics of the biopsy cases examined

From: The chronically inflamed central nervous system provides niches for long-lived plasma cells

Sample ID

Diagnosis

Presence CD138+ Ki67 cells

Age

Treatment

Time from first symptoms to biopsy

MS 1

Acute multiple sclerosis

+

50

none

4 weeks

MS 2

Acute multiple sclerosis

+

22

High dose steroids two weeks prior to biopsy

8 weeks

MS 3

Secondary progressive multiple sclerosis

+

66

Mitoxanthrone

14 years

MS 4

Acute multiple sclerosis

+

58

unknown

9 years

OND 1

Anti-GABA-B receptor encephalitis

+

50

unknown

unknown

OND 2

Whipple’s disease

+

40

unknown

2 years

OND 3

Tuberculosis

+

49

none

unknown

OND 4

Progressive multifocal leukoencephalopathy after immune reconstitution syndrome (PML-IRIS)

+

54

anti-HIV (HAART)

unknown

OND 5

IgG4-related disease

+

45

none

inknown

  1. MS multiple sclerosis, OND other neurological disease