The chronically inflamed central nervous system provides niches for long-lived plasma cells

Table 1 Characteristics of the biopsy cases examined

Sample ID	Diagnosis	Presence CD138⁺ Ki67⁻ cells	Age	Treatment	Time from first symptoms to biopsy
MS 1	Acute multiple sclerosis	+	50	none	4 weeks
MS 2	Acute multiple sclerosis	+	22	High dose steroids two weeks prior to biopsy	8 weeks
MS 3	Secondary progressive multiple sclerosis	+	66	Mitoxanthrone	14 years
MS 4	Acute multiple sclerosis	+	58	unknown	9 years
OND 1	Anti-GABA-B receptor encephalitis	+	50	unknown	unknown
OND 2	Whipple’s disease	+	40	unknown	2 years
OND 3	Tuberculosis	+	49	none	unknown
OND 4	Progressive multifocal leukoencephalopathy after immune reconstitution syndrome (PML-IRIS)	+	54	anti-HIV (HAART)	unknown
OND 5	IgG4-related disease	+	45	none	inknown

ISSN: 2051-5960