Skip to main content

Table 4 Epilepsy-associated genes previously reported to be epigenetically regulated

From: Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons

Epilepsy-ass. Gene Previously described epigenetic modification Organism and Experimental condition Reference
Bdnf DNA methylation Rat HC primary neuronal culture (high K+) [11]
H3/H4 acteylation Rat ECS model [18]
DNA methylation Rat SE model (KA) [13]
Chromatin remodeling Rat SE model (KA) [48]
c-Fos H3 phosphorylation Mouse SE model (KA) [49]
H3/H4 acetylation Rat ECS model [18]
H4 acetylation Mouse SE model (KA) [17]
Cpa6 DNA methylation Human TLE-HS [8]
Creb H3/H4 acetylation Rat ECS model [18]
Gria2 H4 acetylation Rat SE model (PILO) [15]
Grin2a H4K12 acetylation Animal models of AD [30]
DNA methylation Human Depression [31]
Grin2b DNA methylation Rat SE model (KA) [13]
Reelin DNA methylation Human TLE-HS [10]
Genome-wide alterations DNA methylation Rat SE model (PILO) [50]
Rat SE model (KA) [51]
Rat SE model (KA) [14]
Mouse SE model (KA) [51]
Human TLE-HS [12]
Rat SE model (SSSE), Rat TBI model, and Rat SE model (PILO) [9]