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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: A novel vector for transgenesis in the rat CNS

Fig. 6

RaPrnp vector does not exhibit ectopic transgene expression in rat glia. Cortical layers IV and V (a, d, g, and j), CA1 region (b, e, h, and k), and CA3 region (c, f, i, and l). Immunofluorescence for EGFP driven by the RaPrnp vector (ac), astroglial marker Gfap (df), and microglia marker Iba1 (gi) shows no co-localization in Tg12084 rat brains in cortical or hippocampal regions. Merged images (j, k, and l). Scale bar (100 μM) in (a) corresponds to (d), (g), and (j). Scale bar (100 μM) in (b) corresponds to (c), (e), (f), (h), (i), (k), and (l)

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