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Table 1 Demographic and postmortem data from the study subjects

From: Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case

Case # Postmortem diagnosis Age at death Gender Braak stage for NFTs [3] CERAD score [37] Figure
Study case PD 71 M II A 1, 2, 3
BG AD#1 AD 51 F VI C 4
BG AD#2 AD 90 F VI C 4
BG AD#3 AD 64 F VI C N/A
BG AD#4 AD 86 M VI A N/A
BG CTL#1 CTL 58 F I 0 4
BG CTL#2 CTL 92 M II 0 4
BG CTL#3 CTL 73 F I 0 N/A
BG CTL#4 CTL 94 M I 0 N/A
BG PSP#1 PSP 69 M I 0 4
BG PSP#2 PSP 68 M II 0 N/A
BG PiD PiD 62 M I A 4
BG DLB DLB 76 M I 0 N/A
CP#1 CTE 40 M I 0 5
CP#2 VaD 95 M I 0 N/A
CP#3 AD 79 F VI C 5
CP#4 AD 73 F VI C N/A
CP#5 DLB 62 M III B N/A
CP#6 AD 91 F IV C N/A
HE#1 CAA, AD 71 M VI C 6
HE#2 CAA 87 M III B 6
  1. Abbreviations: AD Alzheimer’s disease, BG basal ganglia, CAA cerebral amyloid angiopathy, CERAD Consortium to Establish a Registry for Alzheimer’s disease, CP choroid plexus, CTE chronic traumatic encephalopathy, CTL control, DLB dementia with Lewy bodies, F female, HE hemorrhage, M male, NFT neurofibrillary tangle, NP neuritic plaques, PD Parkinson’s disease, PiD Pick disease, PSP progressive supranuclear palsy, VaD vascular dementia