| |
FTLD
|
FTLD-ALS
|
ALS
|
|---|
|
N (% male)
|
23 (52%)
|
23 (57%)
|
15 (53%)
|
|
Age at death (year)
|
65 ± 8a
|
67 ± 8a
|
71 ± 8
|
|
Age at onset (year)
|
59 ± 8a
|
63 ± 8a
|
70 ± 7
|
|
Disease duration (year)
|
6 ± 4a
|
4 ± 3
|
2 ± 2
|
|
Postmortem delay (hours)
|
25 ± 23
|
25 ± 17
|
22 ± 10
|
|
bvFTD/SD/PNFA/FTD unspecified/AD (n)
|
21/0/0/1/1
|
17/2/2/1/1
|
N/A
|
|
C9ORF72 carrier % (n)
|
48% (11)a
|
39% (9)a
|
0% (0)
|
|
GRN carrier % (n)
|
35% (8)a
|
0% (0)b
|
0% (0)b
|
-
DD Disease duration (years), DO Disease onset (years), PMD postmortem delay (hours), bvFTD behavioral variant frontotemporal dementia, SD semantic dementia, PNFA progressive non-fluent aphasia, AD Alzheimer’s disease, N/A not applicable.a
p < 0.05 compared to ALS, b
p < 0.05 compared to FTLD
