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Fig. 9 | Acta Neuropathologica Communications

Fig. 9

From: CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 N141I neurons

Fig. 9

Intrinsic electrophysiological properties of BFCNs. Summary data on all recorded BFCNs from five groups. Ninety-four neurons (22 wild-type control, 21 familial control, 18 AD1, 28 AD2 and 5 iAD1_control). Histograms show individual values from each neuron (circle) and group means (bars) for membrane resistance (a), capacitance (b), resting potential (c) and rheobase current (d). Statistical significance was tested with ANOVA and Tukey’s post hoc comparisons

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Acta Neuropathologica Communications

ISSN: 2051-5960

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