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Table 1 Demographic, clinical and autoantibody profile of patients whose CSF samples were used in the study

From: Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling

 

NMO

CNS SLE #1

CNS SLE #2

CNS SLE #3

CNS SLE #4

Age

52

59

60

65

49

Sex

Female

Female

Female

Female

Female

SLE duration (years)

0

6

19

9

8

SLEDAI

0

12

12

9

12

Neuropsychiatric manifestations

None

Psychosis Cognitive Dysfunction Vasculitis

Headaches Vasculitis

Depression Cognitive Dysfunction Vasculitis

Anxiety Cerebrovascular Diseases

Serum ANA staining pattern

Negative

Homogenous +

Homogenous +++

Homogenous ++

Speckle +++

Serum anti-AQP4 Positivity

Positive

Negative

Negative

Negative

Negative

Serum anti-dsDNA (g/l)

Negative

163.72

514.44

297.88

25.7

CSF anti-dsDNA (g/l)

Negative

49.46

253.61

77.85

13.46