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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling

Fig. 3

Post-surgery effects of CSF administration on body weight and home-cage behavior in the Integrated Behavioral Station, INBEST. a Treatment with lupus CSF was accompanied by a transient, but significant reduction in body weight when CSF infusion began 4 days after pump implantation. In comparison to control mice treated with NMO CSF, experimental animals exposed to CNS SLE CSF (b) drank less water and (c) consumed less food in INBEST during the 10-h testing period (Days 4 – 18). They also showed (d) lower running wheel activity levels, (e) prolonged stay in the shelter, and (f) decreased ambulation in the home-cage environment (n = 8 mice/group)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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