Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration

Table 1 Cohort characteristics

n	63
FTLD Type (A, B, C, E)	17, 21, 20, 5
Age onset	62.1 (9.2)
Age Death	68.8 (10.2)
Sex (m, f)	32, 31
Brain Wt	1110.0 g (188.6)
GRN Cases	12
C9orf72 Cases	17
Clinical Diagnosis
AD	8
ALS	3
CBD	3
FTD-bvFTD	22
FTD-NOS	14
FTD-PPA	12
MID	1
PSP	1
Primary Neuropath Diagnosis	FTLD-TDP
Secondary Neuropath Diagnosis
AD	9
AGD	5
ALS	1
HS	2
LBD	1
None	21
PART	24

All data are expressed as mean (standard deviation). Clinical diagnoses reflect a patient’s diagnosis at time of death. AD alzheimer’s disease, AGD argyrophilic grain disease, ALS amyotrophic lateral sclerosis, CBD corticobasal syndrome, FTD-bvFTD behavioral variant FTD; FTD-NOS FTD not otherwise specified, FTD-PPA primary progressive aphasia, HS hippocampal sclerosis, LBD lewy body dementia, MID multi-infarct dementia, PART primary age-related tauopathy, PSP progressive supranuclear palsy

ISSN: 2051-5960