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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: RNA biology of disease-associated microsatellite repeat expansions

Fig. 2

Effects of repeat expansion sequence on transcription. Repeat expansion sequences can perturb transcription by a epigenetic silencing, b inducing or facilitating bidirectional transcription, c reduced transcription kinetics, or d generating transcripts that can potentially be processed into small RNAs that could guide degradation or silencing of various complementary RNAs, including the xtrRNA itself

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