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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas

Fig. 4

a) All gliomas included in this study showed statistically different survival. b) Among patients with grade III anaplastic astrocytoma (AA), the IDH-mutant group showed remarkably better survival than IDH-WT group. c) The IDH-mutant grade IV GBM group had significantly better survival compared to the IDH-WT GBM group. d) Of all patients with grade III and IV astrocytic tumors, MGMTp-methylated groups have statistically better survival (P = 0.017). e and f) However, when GBM is subdivided into IDH-mutant and IDH-WT, MGMTp-methylation has a modest survival effect (P = 0.051 and P = 0.076, respectively). These results indicate there is no bias effect associated with our group

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