Skip to main content
Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Fig. 5

Immunocytochemistry of representative tau pathology in human AD brain and JNPL3 Tg mice with new antibodies 2D1 and 7F2. Immuno-reactivity of previously characterized phospho-tau antibodies AT8 and new tau antibodies 2D1 or 7F2 in the hippocampus of a control individual or a subject with AD, and in the spinal cord of 12 month old nTg and JNPL3 Tg mice. Arrows indicating NFTs in human brain or NFT-like inclusion pathology in JNPL3 mice. Asterisk depicting dystrophic neurites within senile plaques. Bar = 100 μm, and 200 μm for insets

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us