Fig. 5

Behavioral assessment of motor functions. a Measurement of the total distance in the open field paradigm at 3 and 6 months revealed no change between AAV1-αsyn and AAV-venus. At 3 months of age AAV1- αsyn seem to perform better in motor coordination and balance tasks (b, c, d) relative to control group (AAV-venus) however, no difference at a later stage was observed. Both groups were able to stay on the accelerating rotarod (b) go down the pole test (c), and cross the beam walk without slip/errors (d). Data are shown as mean ± S.E.M, n = 12–15 per genotype/ per age, two-way ANOVA, post-hoc Bonferroni