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Table 3 Median values with interquartile range for hnRNP E2 immunostaining of pathological inclusions, neuronal nuclei and cytoplasm in frontal and temporal cortex, and dentate gyrus of hippocampus, for each pathological subgroup

From: Heterogeneous ribonuclear protein E2 (hnRNP E2) is associated with TDP-43-immunoreactive neurites in Semantic Dementia but not with other TDP-43 pathological subtypes of Frontotemporal Lobar Degeneration

   Frontal cortex  
Group E2 inclusions E2 nucleus E2 cytoplasm
FTLD-TDP type A 0 (0-0) 1 (0-1) 1 (0-2)
FTLD-TDP type B 0 (0-0) 0.75 (0-1.25) 1 (0-1.25)
FTLD-TDP type C 1 (1-2) 1 (0-3) 1 (0.5-2)
FTLD-tau 0 (0-0) 2 (1-2) 1 (0-2)
Healthy Controls 0 (0-0) 1.5 (0-3) 1.5 (0-2.25)
  Temporal cortex
E2 inclusions E2 nucleus E2 cytoplasm
FTLD-TDP type A 0 (0-0) 1 (0-1) 1 (0-2)
FTLD-TDP type B 0 (0-0) 0.75 (0-1.25) 1 (0-1.25)
FTLD-TDP type C 1 (1-3) 2 (0-3) 2 (0.5-3)
FTLD-tau 0 (0-0) 2 (1-2) 1 (0-2)
Healthy Controls 0 (0-0) 1.5 (0-3) 1.5 (0-2.25)
  Dentate Gyrus
E2 inclusions E2 nucleus E2 cytoplasm
FTLD-TDP type A 0 (0-0) 1 (0-1) 1 (0-2)
FTLD-TDP type B 0 (0-0) 0.75 (0-2) 1 (0-2)
FTLD-TDP type C 2 (0-3) 2 (0-3) 2 (0-3)
FTLD-tau 0 (0-0) 1 (0-3) 1 (0-2)
Healthy Controls 0 (0-0) 1.5 (0-3) 1.5 (0-2.25)
  TDP-43 inclusions
Frontal cortex Temporal cortex Dentate Gyrus
FTLD-TDP type A 3 (2-3) 3 (2-3) 1 (1-1.25)
FTLD-TDP type B 2 (2-3) 2 (2-3) 2 (1-3)
FTLD-TDP type C 2 (2-3) 3 (2-3) 3 (2-3)
FTLD-tau 0 (0-0) 0 (0-0) 0 (0-0)
Healthy Controls 0 (0-0) 0 (0-0) 0 (0-0)