Fig. 2
From: PLGF, a placental marker of fetal brain defects after in utero alcohol exposure
Effects of in utero alcohol exposure on protein expression of members from the VEGF/PLGF family. Quantification by Western blot of the effects of alcohol administered during the last gestational week on the placental expression of VEGF-A (a), PLGF (b), sVEGF-R1 (c), mVEGF-R1 (d), VEGF-R2 (e) and CD31 (f) at GD20. *p < 0.05 vs the control group using the unpaired t test. (g, h) Immunohistochemistry experiments illustrating the distribution of VEGF-R2 in the syncytiotrophoblast layers of the placenta co-labelled with Glut-1. Hoechst was used to label nuclei. (i) Quantification by ELISA of PLGF levels in the microdissected labyrinth zone of control and alcohol-exposed placentae. **p < 0.01 vs the control group using the Mann-Whitney test