Fig. 2

2D diffuse glioma plots with accompanying chromosomal ideograms. a The two main clusters on the right contain mutations in the IDH1 and IDH2 genes, as shown by the purple edges connecting the gene with corresponding patients. The IDH-mutant upper right cluster also carries the majority of (b) TP53 and (c) ATRX gene mutations. d The IDH-mutant lower right cluster contains gliomas that harbor the oligodendroglioma-specific 1p/19q codeletion, as demonstrated by orange edges connecting low level copy loss chromosomal regions with corresponding affected patients. This cluster also contains a majority of the IDH2 mutations