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Table 1 Levels of phospholipids detected by 31P NMR in myelin purified from whole A53T α-Syn and control mouse brains

From: Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss

  Control A53T
α-Syn
P
PA 0.56 ± 0.16 0.90 ± 0.08 0.02*
PC 5.8 ± 1.4 10.5 ± 1.6 0.02*
PE 3.1 ± 1.0 4.9 ± 1.8 0.06
PI 0.4 ± 0.2 0.8 ± 0.2 0.02*
PS 2.6 ± 0.9 4.6 ± 0.5 0.05*
PE-plasm 6.6 ± 1.9 11.5 ± 3.3 0.03*
SPH 0.8 ± 0.3 1.7 ± 1.1 0.12
  1. Table 1 Calculated phosphorus signals for assigned phospholipids detected in lipid extracts of purified myelin from whole A53T α-Syn and control mice (in μmol per mg purified myelin, n = 5 mice). PA phosphatidic acid, PC phosphatidylcholine, PE phosphatidylethanolamine, PI phosphatidylinositol, PS phosphatidylserine, SPH sphingomyelin; and PE-plasm., phosphatidylethanolamine-plasmalogen; *P < 0.05, one-way ANOVA