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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene

Fig. 2

Immunostaining for p62 (a-c) and hnRNP A3 (d-f) in dentate gyrus (a,d) and CA4 region (b,e) of hippocampus, and in cerebellum (c,f), in cases of FTLD-TDP associated with expansions in C9orf72 gene. There are abundant p62-immunoreactive neuronal cytoplasmic inclusions in dentate gyrus (a) and CA4 region (b) of hippocampus, and in cerebellum (c), though only a small proportion of cells in dentate gyrus show similar appearing hnRNP A3-immunoreactive inclusions (arrowed in d), but none are present in CA4 region (e) or cerebellum (f). Immunoperoxidase, microscope magnification, ×400

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Acta Neuropathologica Communications

ISSN: 2051-5960

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