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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

Fig. 2

The integrity of nigro-striatal dopaminergic neurons is preserved in G2019S knock-in (KI) mice. Stereological count of nigral DA neurons (a) and density of tyrosine hydroxylase (TH) positive striatal nerve terminals (b), with representative images, in 12-month-old G2019S KI mice and age-matched WT littermates. Western blotting analysis of striatal TH levels in 12-month-old G2019S KI mice and age-matched WT controls (c). Data are expressed as absolute values and are means ± SEM of 8 (a-b) and 4 (c) animals per group

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