Skip to main content
Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice

Fig. 5

Characterization and result of the functional analysis of module M17 (grey60). a M17 is significantly associated to Novel Place (p >2.9E-04, r = −74), Rotarod (p > 4.3E-03, r = −0.62) and Beam Transversal (p > 3.6E-03, r = 0.63) as well as GLT1 (p > 2.3E-02, r = −0.52) and pSer31TH (p > 1.1E-02, r = −0.57). b The ME expression profile reveals variable expression in WT-Veh, up-regulation in ASO-Veh, and a down-regulation in WT-NSC and ASO-NSC groups. Based on the mean MEs, this module appears to be related to alpha-synuclein pathology which is rescued by NSC transplantation (all functional annotations can be found in Additional files 7, 8, 9 and 19)

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us