Fig. 4
From: A novel form of necrosis, TRIAD, occurs in human Huntington’s disease
YAP/YAPdeltaC are decreased in cortical neurons of postmortem human HD patients. a YAP (upper panels) and YAPdeltaC (lower panels) staining in NeuN-positive neurons in the cerebral cortex of HD and non-neurological disease control patients. Both of the YAP and YAPdeltaC signals were decreased in HD than control. The right graphs show mean + SEM of YAP/YAPdeltaC signal in a neuron (mean intensity/pixel). ***: p < 0.001 in Student’s t-test. b YAP (upper panels) and YAPdeltaC (lower panels) staining in MAP2-positive neurons in the cerebral cortex of HD and non-neurological disease control patients. Both of the YAP and YAPdeltaC signals were decreased in HD than control. The right graphs show mean + SEM of YAP/YAPdeltaC signal in a neuron (mean intensity/pixel). **: p < 0.01, ***: p < 0.001 in Student’s t-test