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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: A novel form of necrosis, TRIAD, occurs in human Huntington’s disease

Fig. 4

YAP/YAPdeltaC are decreased in cortical neurons of postmortem human HD patients. a YAP (upper panels) and YAPdeltaC (lower panels) staining in NeuN-positive neurons in the cerebral cortex of HD and non-neurological disease control patients. Both of the YAP and YAPdeltaC signals were decreased in HD than control. The right graphs show mean + SEM of YAP/YAPdeltaC signal in a neuron (mean intensity/pixel). ***: p < 0.001 in Student’s t-test. b YAP (upper panels) and YAPdeltaC (lower panels) staining in MAP2-positive neurons in the cerebral cortex of HD and non-neurological disease control patients. Both of the YAP and YAPdeltaC signals were decreased in HD than control. The right graphs show mean + SEM of YAP/YAPdeltaC signal in a neuron (mean intensity/pixel). **: p < 0.01, ***: p < 0.001 in Student’s t-test

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