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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G

Fig. 6

NMO pathology in optic nerves and brain of CD59−/− rats following intracisternal injection of AQP4-IgG. a. Immunofluorescence of indicated markers in optic nerves at 3 days after AQP4-IgG injection. Data shown for 3 rats per genotype. b. Immunofluorescence of indicated markers near the brain surface (‘cortex’) and around ventricles (‘peri-vent’) at 3 days after AQP4-IgG injection. c. Distribution of AQP4-IgG at 2 h after intracisternal injection visualized with an anti-human secondary antibody

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