Skip to main content
Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G

Fig. 4

Increased NMO pathology in CD59−/− rats following intracerebral injection of AQP4-IgG. a. Intracerebral injection model showing stereotaxic microneedle injection of AQP4-IgG (or control IgG). b. Immunofluorescence of indicated markers in rat brain at 7 days after AQP4-IgG (or control IgG) injection. Lesion areas indicated by white dotted boundary. c. AQP4, GFAP and MPB immunodeficient areas normalized to hemisphere areas (mean ± S.E.M., 6 rats per genotype, **P < 0.01)

Back to article page