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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy

Fig. 4

Combined treatment modulates behavioral changes in MBP-α-syn transgenic mice. Non-tg and tg animals treated with LV-control or LV-CD5-D5-ApoB, and vehicle or lenalidomide were analyzed in the open field test. a Total activity, measured as total beam breaks. b Rearing, measured as total beam breaks. c Thigmotaxis, measured as the percentage of time spent in the periphery. Results are presented as average ± SEM. # p < 0.05 when comparing vehicle/LV-control-treated tg mice to single or multi-treated tg mice

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