Table 4 ALSci pathology
Stain | Frontal | Cingulate | Hippocampus | Dentate | Entorhinal | Amygdala | BG | SN |
|---|---|---|---|---|---|---|---|---|
Neuronal | ||||||||
pThr175 | ± (4/5) | ± (2/5) | ± (5/5) | + (1/5) | + (4/4) | + (1/1) | - (0/5) | - (0/3) |
PHF | + (2/4) | ± (3/3) | ± − + (4/4) | ± − + (2/4) | ± − ++ (4/4) | ± − ++ (2/2) | - (0/5) | ± (2/2) |
pSer208,210 | ± (2/5) | ± (3/5) | ± − ++ (4/5) | ± (1/5) | ± − ++ (3/4) | + (1/1) | - (0/5) | - (0/3) |
pThr217 | ± (5/5) | ± − + (3/5) | ± − ++ (5/5) | ± − ++ (3/5) | ± − ++ (5/5) | + (1/1) | - (0/5) | ± − + (2/2) |
Glial | ||||||||
pThr175 | ± − ++ (2/5) | ± − ++ (2/5) | - (0/5) | - (0/5) | ± (1/4) | - (0/1) | ± − + (2/5) | - (0/3) |
PHF | ± − ++ (4/4) | ± − ++ (2/3) | - (0/4) | - (0/4) | - (0/4) | + (1/2) | ± (3/5) | - (0/2) |
pSer208,210 | ++ (4/5) | ++ (2/5) | - (0/5) | - (0/5) | ± (1/4) | - (0/1) | ± − + (4/5) | ± (1/3) |
pThr217 | ++ − +++ (5/5) | +++ (2/5) | ++ (2/5) | - (0/5) | ± (1/5) | - (0/1) | + − ++ (5/5) | - (0/2) |
Neuritic | ||||||||
pThr175 | ± − + (3/5) | ± − + (2/5) | ± − + (3/5) | ± − ++ (4/5) | ± − ++ (4/4) | - (0/1) | ± (4/5) | ± (1/3) |
PHF | ± − + (2/4) | ± − + (3/3) | ± − + (3/4) | ± (3/4) | ± − ++ (4/4) | ± − ++ (2/2) | ± (2/5) | ± (2/2) |
pSer208,210 | ± − + (2/5) | ± (3/5) | ± (4/5) | ± (2/5) | ± − ++ (4/5) | + (1/1) | ± (1/5) | ± (1/3) |
pThr217 | ± − ++ (5/5) | ± − ++ (2/5) | ± − + (4/5) | ++ (2/5) | + − +++ (5/5) | + (1/1) | ± (3/5) | ± − ++ (2/2) |