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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity

Fig. 6

ENSA expression levels are reduced in the cingulate gyrus region of a subset of DLB patients. Tissue samples consisted of the cingulate gyrus region of DLB patients and aged-matched controls from two cohorts, provided by GIE Neuro-CEB (a, b) and Massachusetts General Hospital (c, d). The tissues were homogenized and examined for ENSA expression via Western blotting. (a, c) Images of Western blots probed with a primary antibody specific for human ENSA (upper panel), β-3-tubulin (middle panel), or β-actin (lower panel). (b, d) Bar graphs showing relative ENSA expression levels determined via densitometric analysis of Western blots for the individual cohorts. ENSA band intensities were normalized to the corresponding β-3-tubulin signals and divided by the mean value obtained for the control samples. The data are presented as the mean ± SEM, n = 4, **p < 0.01, two-tailed Student’s t-test

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