|
Characteristic
|
NCI (n = 18)
|
MCI (n = 9)
|
AD (n = 7)
|
|---|
|
Age at death (yrs)
|
86.3 (6.4)
|
84.9 (6.8)
|
92.4 (4.7)
|
|
Male : Female
|
6 : 12
|
5 : 4
|
2 : 5
|
|
Education (yrs)
|
17.8 (3.2)
|
18.0 (1.8)
|
17.9 (2.1)
|
|
Post mortem interval, median (IQR)
|
5.6 (5.3–6.3)
|
5.1 (4.5–7.3)
|
5.8 (4.5–13.3)
|
|
Apolipoprotein E ε4, n (%)
|
3 (16.7%)
|
2 (11.1%)
|
0
|
|
Mini mental state exam (MMSE)
|
28.3 (1.8)
|
26.7 (1.9)
|
14.4 (8.3)
|
|
Cognitive test scores
|
|
Global Cognitive Scores
|
0.03 (0.4)
|
−0.4 (0.5)
|
−1.6 (0.8)
|
|
Episodic memory
|
0.4 (0.6)
|
−0.3 (0.9)
|
−2.2 (1.3)
|
|
Working memory
|
−0.02 (0.5)
|
−0.4 (0.8)
|
−0.8 (0.4)
|
|
Semantic memory
|
−0.1 (0.6)
|
−0.3 (0.6)
|
−1.3 (0.9)
|
|
Visuospatial activity
|
−0.1 (0.6)
|
−0.4 (0.9)
|
−1.2 (0.3)
|
|
Perceptual Speed
|
−0.3 (0.5)
|
−0.9 (0.7)
|
−1.6 (0.4)
|
|
Braak Stages, n (%)
|
|
0
|
1 (5.6%)
|
0
|
0
|
|
I
|
1 (5.6%)
|
1 (11.1%)
|
0
|
|
II
|
0
|
2 (22.2%)
|
1 (14.3%)
|
|
III
|
10 (55.6%)
|
3 (33.3%)
|
1 (14.3%)
|
|
IV
|
6 (33.3%)
|
3 (33.3%)
|
1 (14.3%)
|
|
V
|
0
|
0
|
4 (57.1%)
|
- Data represent the mean and (SD). For Braak stage the number of cases and the % in each group (NCI, MCI or AD)
