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Table 1 Demographics and clinical characteristics of the study groups

From: Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment

Characteristic NCI (n = 18) MCI (n = 9) AD (n = 7)
Age at death (yrs) 86.3 (6.4) 84.9 (6.8) 92.4 (4.7)
Male : Female 6 : 12 5 : 4 2 : 5
Education (yrs) 17.8 (3.2) 18.0 (1.8) 17.9 (2.1)
Post mortem interval, median (IQR) 5.6 (5.3–6.3) 5.1 (4.5–7.3) 5.8 (4.5–13.3)
Apolipoprotein E ε4, n (%) 3 (16.7%) 2 (11.1%) 0
Mini mental state exam (MMSE) 28.3 (1.8) 26.7 (1.9) 14.4 (8.3)
Cognitive test scores
 Global Cognitive Scores 0.03 (0.4) −0.4 (0.5) −1.6 (0.8)
 Episodic memory 0.4 (0.6) −0.3 (0.9) −2.2 (1.3)
 Working memory −0.02 (0.5) −0.4 (0.8) −0.8 (0.4)
 Semantic memory −0.1 (0.6) −0.3 (0.6) −1.3 (0.9)
 Visuospatial activity −0.1 (0.6) −0.4 (0.9) −1.2 (0.3)
 Perceptual Speed −0.3 (0.5) −0.9 (0.7) −1.6 (0.4)
Braak Stages, n (%)
 0 1 (5.6%) 0 0
 I 1 (5.6%) 1 (11.1%) 0
 II 0 2 (22.2%) 1 (14.3%)
 III 10 (55.6%) 3 (33.3%) 1 (14.3%)
 IV 6 (33.3%) 3 (33.3%) 1 (14.3%)
 V 0 0 4 (57.1%)
  1. Data represent the mean and (SD). For Braak stage the number of cases and the % in each group (NCI, MCI or AD)